The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show promotes a healthy world through transparent conversations. The show focuses on educating listeners about health and wellness, covering both physical and mental aspects. Dr. Gabrielle Lyon, a Washington University fellowship-trained physician, hosts the show and works with innovators, mavericks, and Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.
Episodes
The Testosterone Myth Men Have Been Lied To About
You were told your testosterone is "normal" so why do you still feel exhausted, weak, and off? The number on your lab report was never built for you, and your own genetics may be the reason it doesn't match how you feel.In this solo episode, Dr. Gabrielle Lyon discusses:Why the standard 300–1000 ng/dL range ignores your age, comorbidities, and genetics, and why two men with identical labs can feel
Is the Protein RDA Too Low for You? What 40 Years of Studies Show - Dr. Don Layman & Dr. Heather Leidy | GLS #214
The July Forever Strong Foundations Challenge begins July 6, 2026. This 4-week challenge is designed to help you build a stronger, more energized you through sustainable nutrition, training, and lifestyle habits. Register here: https://bit.ly/4gCmoNR For 40 years you've been told 0.8 grams of protein per kilogram is "enough" but the scientists who contributed the reports behind the new 2025–2030 D
Nobody Tells You What GLP-1s Do to Your Sex Drive | GLS #213
The receptor that switches off your appetite on a GLP-1 drug is the same one wired into your reward circuitry, your hormones, and your blood vessels, which means when you turn down hunger, something else may be getting turned down too, and for most people taking these drugs, nobody ever checked.In this solo episode, Dr. Gabrielle Lyon discusses:Why the same drug class can improve sexual function i
Why Strength Beats Cardio After 50: Muscle, Longevity & Bone Density - Lisa Smith-Batchen
You might think more cardio is the key to aging well but Lisa Smith-Batchen, who has run 135 miles through Death Valley ten times, says it's strength that actually carries you through the decades.In this episode, Dr. Gabrielle Lyon sits down with Lisa Smith-Batchen, one of the most decorated ultra-endurance athletes in American history and a 10-time Badwater 135 finisher, to discuss:Why being stro
Laura Horvath, Chris Hinshaw & James Sprague: What Separates Champions From Everyone Else
What does it actually mean to win at the highest level? In this powerful compilation, I’m with 2024 CrossFit Games champion James Sprague, 2023 CrossFit Games champion Laura Horvath, and legendary endurance coach Chris Hinshaw to unpack the mental game behind elite performance, the vulnerability that follows victory, and why champions are often more fragile in the moments just after they win. What
What Your ED Is Really Telling You About Your Heart, Blood Sugar & Hormones - Urology Roundtable
Most men think erectile dysfunction is a bedroom problem and low testosterone is just a fact of getting older. This roundtable makes the case that both are early warning lights for your heart, your metabolism, and your long-term health and that ignoring them can cost you a decade.In this episode, Dr. Gabrielle Lyon sits down with urologists and men's health specialists Dr. Mohit Khera, Dr. Larry L
How to Stay Calm in a Crisis and Why Detachment Is a Trainable Skill - Jamie Cochran
Your ego isn’t the enemy, but if you’re not actively controlling it, it is running your team, your home, and your most important relationships. Jamie Cochran, COO of Echelon Front, has spent 13 years helping leaders fix the root cause most of them never look for.The Women’s Leadership Assembly live event runs January 5–7, 2027 in Palm Springs. A free monthly webinar series runs year-round. More de
Penis Health, What Every Man Needs to Know - Dr. Amy Pearlman
Most men think erectile dysfunction is a bedroom problem. It's actually one of the earliest warning signs of cardiovascular disease, capable of showing up three to five years before a heart attack.In this episode, Dr. Gabrielle Lyon sits down with Dr. Amy Pearlman, a urologist trained in men's sexual health, to discuss:Why ED is a symptom of vascular health, not a standalone disease and how the ar
Your Doctor Is Watching the Wrong Number. LDL, ApoB & Heart Risk Explained. - Dr. Kevin Maki
Most people think the cholesterol number on their lab report tells them whether their heart is at risk. But former National Lipid Association President Dr. Kevin Maki explains that LDL is just one piece of a much bigger picture and focusing on it alone can mean missing the markers that matter most.In this episode, Dr. Gabrielle Lyon sits down with Dr. Kevin Maki, former President of the National L
The Cancer Doctors Keep Missing in Young Adults - Dr. Michelle Pearlman
Colorectal cancer is now the leading cancer killer in adults under 50, and patients in their 20s are presenting with metastatic disease that has nothing to do with family history. Most physicians are still telling young patients with rectal bleeding that it's probably just hemorrhoids and that's costing lives.In this episode, Dr. Gabrielle Lyon sits down with Dr. Michelle Pearlman, a board-certifi
Jocko Willink - Parenting, Apex Kid Myth, Failure, & Leadership
Most parents are quietly paving the road their kids were supposed to learn to walk on by themselves and Jocko Willink has spent 20 years watching what happens when that road is too smooth.In this episode, Dr. Gabrielle Lyon sits down with Jocko Willink, retired Navy SEAL commander, founder of Echelon Front, and bestselling author of Extreme Ownership and Discipline Equals Freedom, to discuss:Why t
Doctors Are Removing Testicles for This | Dr. Susan Macdonald
Most men don't know they have a pelvic floor, and most doctors aren't trained to look for dysfunction in it. The result: testicles are being surgically removed for pain that's actually neuropathic, at double the rate of a far more effective nerve-sparing procedure.In this episode, Dr. Gabrielle Lyon sits down with Dr. Susan Macdonald, a board-certified urologist, surgical program director at Penn
Mark Bell on Fat vs. Carbs, What’s Really Making You Fat?
Most people are chasing the wrong version of strength and paying for it with pain, poor movement, and a body that breaks down faster than it should. In this episode, Dr. Gabrielle Lyon sits down with Mark Bell, elite powerlifter, entrepreneur, and founder of Slingshot, to discuss:Why strength training is essential at every age but most people are defining "strength" too narrowlyHow modern life has
GLP-1 Side Effects, Risks, And Who Should Actually Be Using It | Dr. Christle Guevarra
We are living through one of the most significant shifts in medicine in generations, and most people don’t fully understand what it means. Dr. Christle Guevarra joins me to zoom out on the entire GLP-1 landscape; from the drug’s origins as a modest diabetes treatment in 2005 to today’s third-generation medications still moving through clinical trials, and what all of it means for the future of obe
Dominique Sachse on Aging Well, HRT, and Building Muscle After 50
The moment you decide to show up publicly, you open the door to opinions from people who would never say those things to your face. Dominique Sachse, journalist, author, and content creator who has lived her life on camera for over three decades, gets honest about what it costs to put yourself out there, why online cruelty is a psychology problem more than a content problem, and how “Teflon Dom” d
The Truth about Saturated Fat, Omega-3 Fatty Acids and Total Mortality | Dr. Tom Brenna
Only nine scientists were asked to advise on the 2025 Dietary Guidelines for Americans, and Dr. Tom Brenna was one of them. In this conversation, he pulls back the curtain on how dietary guidelines are actually made, why the process has never been the same twice, and what it was like to watch a decades-old saturated fat recommendation get carried forward despite a lack of evidence supporting it at
GLP-1 Drugs & Bariatric Surgery Explained by a Top Obesity Researcher | Dr. David Allison
In a world flooded with conflicting health advice, how do you actually figure out what’s true? Dr. David Allison, one of the most rigorous scientific minds in obesity and nutrition research, shared the exact framework he uses to evaluate evidence, from peer-reviewed trials to podcast recommendations to AI-generated summaries. He explains the difference between trusting science as a process and tru
Dr. Tommy Wood: Can Cognitive Decline Be Reversed?
Up to 70% of dementia may be preventable, so why aren’t more people talking about what actually drives cognitive decline? In this episode, I’m with Dr. Tommy Wood, neuroscientist and author of “The Stimulated Mind,” to explore the lifestyle levers that protect your brain across a lifetime. Learn how white matter hyperintensities develop and whether they can reverse, what MCTs and ketones actually
HIIT vs. Moderate Intensity Exercise - Which Is Better for Your Health? | Dr. Martin Gibala
Metabolic flexibility is your body’s ability to efficiently burn fat or carbohydrate depending on demand, may be one of the most important and least understood markers of long-term health. In this episode, I’m with Dr. Martin Gibala to explore the emerging science of Fat Max, why mitochondrial quality is central to both performance and longevity, and how sprint interval training produces comparabl
Danica Patrick Opens Up About Breast Implant Illness, Inflammation, and Starting Over
The most decorated woman in motorsports history will tell you she feared losing far more than she loved winning, and that fear is exactly what drove her to the top. In this episode, I’m with racing legend Danica Patrick to unpack the psychology of elite performance, from the “blind faith” that carried her through two decades of racing to the nervous system conditioning she built starting at age 10
Hormone Replacement Therapy, What Every Woman Needs to Know in 2026 | Dr. Heather Hirsch
I’m joined by Dr. Heather Hirsch to debunk the persistent myths surrounding hormone replacement therapy and explain why the 2002 Women’s Health Initiative data was so widely misinterpreted. We discuss how optimized estrogen, progesterone, and testosterone levels can protect your heart, bones, and brain health, helping you move past "normalized suffering" and into a proactive state of longevity. Wh
Male Fertility and Sperm Health: What Your Sex Drive and Testosterone Really Mean | Dr. Michael Eisenberg
Male fertility is declining, and most men have no idea why.In this episode of The Dr. Gabrielle Lyon Show, Dr. Gabrielle Lyon sits down with Dr. Michael Eisenberg, Director of Male Reproductive Health at Stanford University and Chief Medical Advisor of SwimClub, to break down what truly determines sperm health and reproductive success.They discuss:How metformin, GLP-1 medications, testosterone the
Why You Don’t Believe in Yourself (And How to Fix It) | Dr. Shadé Zahrai
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comSelf-doubt holds more people back than lack of skill or intelligence.In this episode, Dr. Gabrielle Lyon sits down with Dr. Shadé Zahrai to explore the science of confidence, self-trust, and peak performance. They break down why confidence comes after action, how self-image shapes success, and the four p
How to Eat for Strength, Metabolism, and Longevity
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comThis episode brings together standout moments from The Forever Strong Experience, packed into one powerful episode.Featuring highlights from:Dr. Mark Hyman – Founder of the Cleveland Clinic Center for Functional Medicine, co-founder and CMO of Function Health, director of The UltraWellness Center, host o
Protein First: How the New Dietary Guidelines Shift Nutrition
Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, Dr. Gabrielle Lyon sits down with Dr. Donald Layman, one of the world’s leading protein researchers and a key contributor to the newly released U.S. Dietary Guidelines. They explore why the old food pyramid failed, how nutrition science became driven by ideology instead of evidence, and
The Forever Strong PLAYBOOK: Your 6-Week Field Manual for Muscle-Centric Longevity
Order The Forever Strong PLAYBOOK: https://drgabriellelyon.com/playbook/Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this solo episode, Dr. Gabrielle Lyon shares the deeper mission behind The Forever Strong PLAYBOOK and the philosophy that has guided her work for decades.This conversation is not about trends, quick fixes, or aesthetics. It is ab
You Don’t Need Confidence, Just Do THIS | Leila Hormozi
Pre-order The Forever Strong PLAYBOOK today to unlock over $400 in free bonuses and learn how to build the muscle, resilience, and metabolic health that actually determine how well you age. https://drgabriellelyon.com/playbook/Want ad-free episodes? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, Gabrielle Lyon sits down with Leila Hormozi to discuss the jo
Willpower vs. Systems: Why Your Diet Fails & How to Fix Your Relationship w/ Food | Sohee Carpenter
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/ Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.com In this episode, Dr. Gabrielle Lyon is joined by Sohee Carpenter, PhD, to explore the complex intersection of psychology, eating behavior, and resistanc
The Gut-Muscle-Immune Axis: How Mitophagy Rewires Your Body for Longevity
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comAre your immune cells aging faster than you are? In this episode, Dr. Gabrielle Lyon sits down with Dr. Anurag Singh, a leading physician-researcher and C
The Joint Health Blueprint: Preventing Arthritis, Frozen Shoulder, and Bone Loss as You Age
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIf you are only focusing on building muscle, you are missing half the equation for long-term mobility. In this mashup episode, Dr. Gabrielle Lyon brings t
Hormone Replacement Therapy Decoded: Why the FDA Removed the Blackbox Warning on HRT
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comThank you to our sponsors: BodyHealth - Use the code LYON20 to get 20% off your first order https://bodyhealth.com/ Manukora - Visit MANUKORA.com/DRLYON
Dr. Jen Ashton on Unimaginable Loss, Mental Health, and Post-Traumatic Growth
If you or someone you know is experiencing suicidal thoughts, emotional distress, or a mental health crisis, call or text 988, or chat via 988lifeline.org. Support is available 24/7. You are not alone, and help is available.Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&
STOP Inflaming Your Body: The #1 Enemy to Egg Quality and Conception
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comDr. Gabrielle Lyon sits down with fertility specialist Dr. Natalie Crawford to tackle the urgent rise in infertility across both men a
Carbs vs. Protein: Which Macronutrient Is Actually More Dangerous to Overconsume?
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comDr. Gabrielle Lyon reveals the biggest mistakes Americans make with their nutrition and body composition, especially after age 40. With 75% of A
Over 70 and Shredded: The Guide to Building Muscle at Any Age | Michelle & Joan MacDonald
Want ad-free episodes and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comBecome a patient: https://strongmedical.com/apply-now/?utm_source=youtube&utm_medium=video&utm_campaign=strongmedical&utm_content=descriptionIn this empowering episode, Dr. Gabrielle Lyon sits down with the incredible mother-daughter duo, Michelle and Joan Mac
TRT: Your Complete Guide to Safe Dosing, Risks, and Boosting Longevity
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this compilation episode, Dr. Gabrielle Lyon is joined by the top experts in Testosterone and men's health treatments. You'll learn:Why aging alone doe
Neuroscientist Explains MDMA and The Science of Social Connection | Dr. Ben Rein Ph.D.
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this fascinating episode, Dr. Gabrielle Lyon talks with neuroscientist Dr. Ben Rein, PhD (author of Why Brains Need Friends), about the science of soci
Sex Therapist explains The Science-Backed Guide to a Better Sex Life | Marianne Brandon
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this explosive episode, Dr. Gabrielle Lyon sits down with relationship expert Marianne Brandon to confront the modern crisis of intimacy and sexual wellness. They
The Menstrual Cycle DECODED: Fertility, PCOS, and the New Science of Hormones
Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, Dr. Gabrielle Lyon sits down with Dr. Heidi van den Brink; one of the only scientists in the world studying the ovarian transit
TRT Risks & Rewards: Your Testosterone Replacement Therapy Questions Answered
In this highly requested AMA, Dr. Gabrielle Lyon addresses the most critical questions surrounding male hormone health. Dr. Lyon tackles the fear, stigma, and misinformation surrounding Testosterone Replacement Therapy (TRT), revealing why a low testosterone level is a major predictor of serious health issues like heart disease, bone fracture, and obesity.She breaks down the cu
The Cancer Scare That Taught Jeremy Miner What Really Matters
In this powerful episode, Dr. Gabrielle Lyon sits down with legendary sales expert and entrepreneur Jeremy Miner to discuss the foundation of success. Jeremy, the founder of Seventh Level, reveals the mental frameworks, communication skills, and commitment required to achieve peak performance in any area of life.Drawing from his own harrowing health scare and decades of experience coaching top per
The Future of Prostate Cancer Treatments & Non-Invasive Techniques with Less Side Effects | Dr. Sanjay Mehta
Join the October Menopause Challenge: https://drgabriellelyon.com/forever-strong-menopause-challenge/Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comWhen you hear the word “radiation,” do you think of c
A Parent's Guide to Vaccines & Obesity: Protecting Your Child in a Confusing World | Dr. Joel Gator
Join the October Menopause Challenge: https://drgabriellelyon.com/forever-strong-menopause-challenge/Pre-Order The Forever Strong PLAYBOOK and receive exclusive bonuses: https://drgabriellelyon.com/playbook/Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comDescriptionIn this episode, Dr. Gabrie
The TRUTH About Makeup, Sunscreen and Skin Cancer | Teo Soleymani
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, Dr. Gabrielle Lyon sits down with Dr. Teo Soleymani, a fellowship-trained skin cancer surgeon and dermatologist, to cut through the noise of the skincare industry. They discuss everything from viral trends like "glass skin" to the science behi
Why Navy SEALs Aren't Scared Like Everyone Else | Rich Diviney
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this powerful episode, Dr. Gabrielle Lyon sits down with former Navy SEAL Commander and author, Rich Diviney, to break down what it takes to thrive under extreme pressure. Rich, author of "The Attributes and Mastering Uncertainty", reveals the psychology of
The Truth About Hormones: Why Every Woman Should Consider Menopause Therapy
Want ad-free episodes, exclusives and access to community Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comIn this episode, I sit down with nutritional physiologist and friend Nick Barringer, PhD, to tackle a crucial, yet often misunderstood, topic: women's hormonal health. We expose the devastating impact of the Women's Health Initiative study and why millions of
Ultimate Fat Loss Guide - Gabrielle Lyon - Mike Israetel - Layne Norton - Don Saladino
In this compilation, Dr. Gabrielle Lyon brings together the top minds in health and fitness to deliver the ultimate guide to fat loss. Featuring the best moments with Dr. Mike Israetel, Dr. Layne Norton, and Don Saladino, this video cuts through the confusion and gives you a no-nonsense, science-backed approach to transforming your body.You’ll hear from the experts on everything from the flawed sc
Cancel Your Fear of Dying: How to Live Fully by Facing Death | Elena Brower
Want ad-free episodes, exclusives and access to Q&As? Subscribe to Forever Strong Insider: https://foreverstrong.supercast.comWe have all heard the sayings and clichés, but what is the truth behind being afraid of dying? In this episode, Dr. Gabrielle Lyon sits down with Elena Brower, a best-selling author, meditation teacher, and hospice volunteer, to discuss the profound topics of impermanen
The Protein Debate: Dr. Layman Reacts to Dr. Gardner's claims on The Huberman Lab
In a powerful episode of the Dr. Gabrielle Lyon show, I sit down with my mentor, Dr. Donald Layman, to directly address some of the most common protein myths. We react to a controversial clip from the Huberman Lab podcast with Dr. Christopher Gardner, offering a different perspective on the conversation about protein intake, metabolic science, and dietary guidelines.Dr. Layman, a pioneer in protei
Erections & Testosterone - Shocking Link to Muscle Mass & Men's Health | Dr Tobias S Kohler
In this groundbreaking episode, Dr. Gabrielle Lyon sits down with Dr. Tobias Kohler, a professor of urology at the Mayo Clinic, to discuss a topic most people are afraid to talk about: men's sexual health.Dr. Kohler shares eye-opening insights, backed by over two decades of clinical experience and research, on the powerful link between foundational health habits and male sexual function. They reve
The Truth About Sleep: Myths, Tips, and Longevity Secrets with Dr. Rebecca Robbins
Are you struggling to get a good night's rest?Do you think you can thrive on just a few hours of sleep? In this eye-opening episode, Dr. Gabrielle Lyon sits down with renowned sleep scientist Dr. Rebecca Robbins to debunk the biggest sleep myths and reveal the profound connection between sleep and your health, longevity, and daily performance. They dive into the science of sleep, from the homeosta
MCAS, POTS & Histamine Intolerance: Hidden Drivers of Chronic Symptoms | Michelle Shapiro, RD
Mysterious symptoms. Confusing diagnoses. Years of being dismissed. In this episode, Michelle Shapiro joins me to unpack the often misunderstood and overlooked world of mast cell activation syndrome (MCAS), histamine intolerance, postural orthostatic tachycardia syndrome (POTS), and hypermobility conditions. Drawing from her own health journey and experience with thousands of clients, Michelle unp
The Truth About Women’s Heart Health | Dr. Martha Gulati
Heart disease is the leading cause of death for women—yet it's still treated like a man’s disease. In this powerful conversation, Dr. Martha Gulati, a cardiologist and pioneer in women’s cardiovascular health, exposes the systemic gaps that leave women underdiagnosed, undertreated, and often unheard. Together, we unpack the critical differences in how heart disease presents in women, why standard
Why Protein Isn’t Always Enough: Anabolic Resistance, Obesity, and Protein Efficiency | Dr. Nick Burd
Muscle health isn’t just about how much protein you eat—it’s about how your body uses it. And for people with obesity or advancing age, that process can become less effective, even with optimal nutrition. In this episode, I am joined by Dr. Nick Burd, one of the world’s leading researchers in muscle metabolism, to unpack the concept of anabolic resistance—when muscle doesn’t respond normally to pr
How to Prevent Heart Disease with Mitochondria, Muscle, and the Endothelial Glycocalyx | Dr. Michael Twyman
Did you know every 40 seconds someone in the U.S. has a heart attack—and 1 in 5 never even see it coming? This week, I am joined by preventive cardiologist Dr. Michael Twyman as we discuss cutting-edge diagnostics, the endothelial glycocalyx, nitric oxide biology, and why muscle mass is your heart’s best friend. Learn the practical steps and questions to ask to protect your heart before symptoms a
Stronger: The Untold Story of Muscle, Strength, and Human Potential | Michael Joseph Gross
In this episode, I’m joined by journalist and author Michael Joseph Gross, whose book, Stronger: The Untold Story of Muscle in Our Lives, reveals the powerful and often overlooked role of muscle in human health and society—tracing its importance from ancient civilizations to modern science. We explore how our understanding of muscle has evolved through history, from symbols of strength and vitalit
Food & Metabolomics: How Your Diet—Starting in Childhood—Shapes Your Brain | Dr. Alexis Wood
In this episode, Dr. Alexis Wood, a leading researcher at Baylor College of Medicine, joins me to unpack insights into childhood nutrition, genetics, and cognitive health. Dr. Wood's work bridges genetics, dietary practices, and brain development, highlighting how early-life nutrition can shape lifelong outcomes. We explore cutting-edge research, practical strategies for parents, and the surprisin
Are Red Meat Warnings Based on Flawed Science? Dr. David Klurfeld on Nutrition Myths and Industry Bias
In this episode, I sit down with Dr. David Klurfeld—longtime USDA scientist and one of the few insiders to publicly challenge the WHO's classification of red meat as a carcinogen. We go deep into the flawed evidence behind the infamous 2015 IARC report, why nutritional epidemiology often fails to prove causality, and how a small group of researchers helped shape global policy with low-quality scie
Why Men’s Fertility Is Declining: The Truth About Testosterone | Dr. Larry Lipshultz
Dr. Larry Lipshultz. is one of the world's leading experts in men's reproductive health. In this week's episode, we discuss testosterone therapy, male fertility, and the hidden environmental factors threatening men’s health. Dr. Lipshultz shares groundbreaking insights into why male fertility is declining, common myths surrounding testosterone and prostate cancer, and innovative strategies to safe
How to Train Your Mind: Ancient Wisdom, Modern Science, and the Mindset of Excellence | Brian Johnson
What if your biggest challenge isn’t motivation but missing structure? In this episode, I sit down with Brian Johnson to unpack the science and philosophy of lasting behavior change. We explore the power of ancient wisdom, stoicism, and the neuroscience of excellence, and why most wellness apps fail to deliver real transformation.Brian shares his personal journey from startup success to creating a
Understanding Heart Rate Variability: Improving Your Health & Performance | Joel Jamieson
When it comes to performance, more isn’t always better. In this episode, I sit down with conditioning expert Joel Jamieson to explore the science of recovery, aerobic fitness, and how to use heart rate variability (HRV) to train smarter. They dive into why elite athletes recover so quickly, the long-term value of zone 2 training, and how HRV reflects your resilience—not just your readiness. Joel s
Why Do Most Diets Fail? The Science of Nutrient Deficiencies | Ty Beal PhD
In this episode, I’m joined by Dr. Ty Beal—global nutrition researcher and Senior Technical Specialist at the Global Alliance for Improved Nutrition (GAIN)—to uncover the hidden epidemic of micronutrient deficiencies worldwide. From food access and affordability to ultra-processed diets and nutrient bioavailability, we explore how modern food systems are failing billions and what needs to change t
Women’s Training & The Menstrual Cycle: What the Science Actually Says | Lauren Colenso-Semple, PhD
In today's episode, I had the chance to speak to muscle physiology researcher and science communicator Dr. Lauren Colenso-Semple. Together, we unpack the common claims around hormones and training—from whether you should change your workouts based on your cycle, to the real effects of fasted cardio and birth control on performance and muscle growth. We also explore how menopause affects body compo
The Truth About Women’s Metabolism, Muscle & Fat Loss at Every Age | Abbie Smith-Ryan, PhD
In this episode, I’m joined by Dr. Abbie Smith-Ryan—one of the leading researchers in exercise physiology and women’s metabolism—to unpack the science of how women should be training through perimenopause, postmenopause, and beyond. We dive into the physiological changes that impact body composition, performance, and recovery—and how to adjust training and nutrition to match.We discuss:How high-in
The Truth About Sweeteners, Seed Oils, and Building Real Strength | Nick Barringer, PhD
This week in the studio, I'm joined by Dr. Nick Barringer—Army Ranger, performance nutrition expert, and one of the sharpest minds in military and metabolic health. Together, we cut through the noise around today's most controversial nutrition topics. If you’ve ever felt whiplash trying to make sense of conflicting headlines, this episode is your science-based compass.What’s really going on with a
Is Ozempic Actually Safe? CEO of Major Pharmacy Speaks Out | Shaun Noorian, CEO
In this episode, I’m joined by Shaun Noorian—engineer, entrepreneur, and CEO of Empower Pharmacy, the largest compounding pharmacy in the world. With compounded GLP-1s making headlines and lawsuits from Big Pharma intensifying, Shaun joins me to pull back the curtain on the regulatory, financial, and ethical storm brewing behind the scenes.Are compounded GLP-1s legal? Safe? Who controls drug prici
GLP-1 & PCOS Breakthroughs: How Ozempic is Changing Women’s Health | Dr. Melanie Cree
In this episode, I’m joined by Dr. Melanie Cree—physician-scientist, pediatric endocrinologist, and one of the leading researchers redefining how we understand and treat Polycystic Ovary Syndrome (PCOS). PCOS affects millions of women, yet it's still underdiagnosed, misunderstood, and often mistreated. Dr. Cree cuts through the confusion, offering a deeply scientific yet compassionate look at what
The Science of Joint Health: How to Keep Your Bones Strong for Life | Dr. Jocelyn Wittstein
In this episode, I’m joined by Dr. Jocelyn Wittstein—orthopedic surgeon, sports medicine expert, and Associate Professor at Duke University—for a powerful and practical conversation about bone and joint health across the lifespan. From the challenges of frozen shoulder and arthritis to the truth about running and menopause hormone therapy, this episode is your definitive guide to staying str
Resilient by Design: A Navy SEAL-Turned-Doctor’s Roadmap to Success | Shane Kronstedt MD
In this episode, I’m joined by Dr. Shane Kronstedt—former Navy SEAL, physician, surgical resident, and most importantly, my husband—for a powerful conversation about discipline, resilience, and the real-life moments that define us. From his early years of martial arts and mixed martial arts to surviving Hell Week and life-or-death missions in Afghanistan and Uganda, Shane shares how pressure creat
Comfort is Destroying Your Health: Why Stress is Not the Enemy | Jeff Krasno
Jeff Krasno’s personal health transformation—reversing diabetes, shedding 60 pounds, and reclaiming his health at age 50—is a masterclass in what he calls “good stress.” In this episode, we dive into the simple but powerful idea that discomfort might just be the medicine we all need. Jeff, the founder of Commune and host of the Commune podcast, shares how fasting, cold exposure, resistance trainin
Steroids & Testosterone: The Science Behind Anabolic Therapies | Nelson Vergel
Nelson Vergel’s story is one of resilience, perseverance, and an unrelenting drive to defy the odds. In the mid-1980s, he was handed what many would have considered a death sentence—an HIV diagnosis at a time when there were no effective treatments, no clear answers, and little hope. Today, he is a beacon of knowledge and empowerment for those seeking to take control of their health, whether they
The Truth About Calories and Weight Loss | Dr. James Hill
Dr. James Hill—a expert on obesity, metabolism, and long-term weight management—joins me this week to unpack the biggest challenges in sustainable fat loss. Dr. Hill has spent decades researching weight control and the factors that determine whether people can keep weight off long-term. We discuss the science behind energy balance, metabolic flexibility, and why long-term weight loss is about more
The Science of Optimizing Your Testosterone | Abraham Morgentaler, MD
In this episode, Dr. Abraham Morgentaler—an expert in urology and hormone health—helps unpack the biggest myths and misconceptions surrounding testosterone therapy for both men and women. He shares his pioneering research on testosterone replacement therapy, challenging outdated fears about its link to prostate cancer and highlighting the latest findings on how hormone therapy can impact overall h
The Truth About Nutrition: How You Can Take a Science-Based Approach | Bradley Johnston PhD
Misinformation in nutrition is rampant. From demonizing red meat to hyping plant-based diets, conflicting advice has left many people confused about what’s truly evidence-based. In this episode, I am joined by Dr. Bradley Johnston, an expert in evidence-based nutrition and public health policies, to separate fact from fiction. With nearly 200 peer-reviewed publications, Dr. Johnston has challenged
Plastic Surgery Myth Busting: The Truth About Breast Implants, Botox, and Beauty Trends | Dr. Kristy Hamilton
In this episode, I sit down with Dr. Kristy Hamilton, a board-certified plastic surgeon, to explore the latest advancements in aesthetic medicine, the impact of social media on beauty standards, and the reality of breast implant illness. Dr. Hamilton shares her expert insights on facial rejuvenation, fat transfer, the safety of fillers, and new biostimulators while debunking common myths around pl
The Ultimate Protein Blueprint: How to Build Strength & Live Longer | Dr. Donald Layman
Today, I welcome Dr. Donald Layman back to The Dr. Gabrielle Lyon Show for a deep dive into his decades of protein research, the flaws in dietary guidelines, and the evolving landscape of nutrition. Together, we explore the real reasons behind the obesity epidemic, why decades of dietary advice have led us astray, and how we can reclaim metabolic health through high-quality protein intake. Dr. Lay
Defying Convention with Low-Carb Performance | Zach Bitter
Today, I welcome ultra-endurance athlete and world record holder Zach Bitter to The Dr. Gabrielle Lyon Show for an insightful conversation on the extreme physical and mental demands of ultra-marathons. Zach shares his mindset strategies for overcoming the inevitable dark moments in long-distance races, including visualization techniques and the importance of mental resilience in performance.We als
Rethinking Protein Guidelines For Optimal Health | Dr. Heather Leidy
Today, I welcome Dr. Heather Leidy to The Dr. Gabrielle Lyon Show for an in-depth conversation about the evolving landscape of nutrition science. Together, they tackle pressing topics like the future of the U.S. Dietary Guidelines, the impact of protein timing, and the importance of protein quality in supporting health and mitigating frailty. Dr. Leidy highlights recent research that explores beha
Unlocking the Secrets of Whole Foods | Dr. Stephan Van Vliet
Dr. Stephan Van Vliet joins us for an enlightening exploration of nutrition, agriculture, and human health. Our discussion navigates the often-overlooked complexities of food production, examining the nutritional differences between pasture-finished and grain-finished beef. We also uncover how maternal nutrition might set the stage for children's future dietary preferences. Dr. Van Vliet introduce
Harnessing Sleep Science For Peak Performance | Dr. Allison Brager
In this episode of The Dr. Gabrielle Lyon Show, I sit down with my friend, Dr. Allison Brager, a neurobiologist, researcher, and active-duty U.S. Army neuroscientist whose work redefines what we know about sleep and human performance. Allison’s expertise goes beyond the usual advice about getting eight hours of sleep. Instead, we explore how to optimize performance and resilience when life doesn’t
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