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Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
Mast Cell Matters: Deep dives on MCAS with Tania Dempsey, MD - Presented by The POTScast
Each episode is a deep dive on Mast Cell Activation Syndrome (MCAS) with a top physician, researcher or other expert who specializes in treating patients with MCAS. Hosted by Johns-Hopkins-trained world renowned specialist Tania Dempsey, MD, we take a practical approach to helping doctors and patients better manage MCAS. We cover the symptoms, testing, diagnosis, treatment, challenges, practical strategies, common comorbidities (e.g., POTS, hypermobility spectrum disorders, ME/CFS, autoimmunity, GI dysmotility), latest research findings and clinical pearls. These episodes are a monthly feature of The POTScast, presented by Standing Up to POTS, a non-profit dedicated to improving life for those with POTS and related chronic illness.
Episodes
GLP-1s in MCAS with Dr. Tania Dempsey
This is a not-to-be-missed episode! Dr. Dempsey discusses the use of GLP-1 medications for MCAS, including her most recent observations and recommendations. This is a follow-up to Dr. Dempsey's free online GLP-1 Masterclass, which covers all the basics. If you have questions for Dr. Dempsey about mast cells and related topics, you can send them to re
Cell membrane health and why it matters for MCAS and beyond with Dr. Melanie Stein and Dr. Tania Dempsey
Dr. Melanie Stein, ND is a licensed Naturopathic Physician in Portland, Oregon and a recognized leader in Cell Membrane Therapy for the treatment of complex and chronic illness. She specializes in restoring health at the cellular level—repairing and revitalizing cell membranes to improve energy production, enhance detoxification, and restore healthy com
More cutting edge treatments (part 2) with Dr. Tania Dempsey
Dr. Dempsey is always looking for new ways to help her complex patients. In this episode Dr. Dempsey discusses how she incorporates treatments with Methylene Blue, peptides, and the Nanovi breathing device. For each one she explains what it is, how it works, the risks and benefits, who is a good candidate, and more.
More information about Dr. Tania De
Pediatric Complex Chronic Illness & Treatment with Dr. Casey Kelley
Dr. Casey Kelley is Board Certified in family and integrative medicine, teaches on the faculty of the Northwestern Medical School, and her care is informed by her own past experience having complex chronic invisible illness. Now she treats some of the very toughest cases, including Lyme, POTS, PANS/PANDAS, MCAS and more. In this episode she and Dr. De
Neurogastroenterologist Zac Spiritos, MD, MPH with Dr. Tania Dempsey
Dr. Spiritos is double board certified in gastroenterologist and internal medicine, and specializes in IBS, gut motility, POTS and the complex conditions and symptoms that go along with it. He and Dr. Dempsey discuss IBS, parasites, SIBO, CD117 staining, GLP-1 drugs for MCAS, his treatment approach, some promising news on the awareness front, and much
Dr. Dempsey on cutting edge treatments she is seeing help complex patients
One of the most common questions we get from listeners is about the novel treatments that Dr. Dempsey mentions, such as therapeutic plasmapheresis exchange (or apheresis), SOT, ozone therapy, UV light blood irradiation and more. In this episode she discusses each treatment: What it is, how it works, the risks and benefits, who is a good candidate, and
Dr. Eboni Cornish on root causes of brain inflammation
This is a not-to-be-missed episode for anyone interested in brain inflammation. Dr. Eboni Cornish, M.D. is Associate Medical Director at Amen Clinics, Fellow and Treasurer of the Board for the International Lyme and Associated Diseases Society (ILADS). With research training at the National Institutes of Health as a Howard Hughes Medical Fellow, she is
Jill Krapf on painful sex, vulvovaginal disorders and mast cells with Dr. Tania Dempsey
Dr. Jill Krapf is a Board-Certified OB/GYN who specializes in genitopelvic pain and skin conditions, is founder of the Center for Vulvovaginal Disorders and co-author of the book When Sex Hurts: Understanding and Healing Pelvic Pain. She is a wealth of knowledge and with Dr. Dempsey they discuss the mechanisms behind these disorders, treatments, plus t
Dr. Greg Plotnikoff on favorite new findings, a thiamin theory and more
Dr. Greg Plotnikoff is a thought leader in dysautonomia/MCAS and complex chronic illness and in this episode he is freshly returned from giving two presentations at the Dysautonomia International Conference. He and Dr. Dempsey discuss what he learned and what he is currently excited/hopeful about, including new data about hypermobility as a potential u
MCAS symptoms “down there” with Dr. Tania Dempsey
MCAS doesn't ignore the nether-regions, so in this episode, Dr. Dempsey discusses symptoms and treatments in the genitourinary and surrounding areas, including some novel uses of antihistamines and mast cell stabilizers, as described in this research article. She also answers listener questions about hormones, hormone replacement, reactions to ultrasou
Todd Maderis, ND on latest tests and treatments for underlying causes
Dr. Todd Maderis is a naturopathic physician in Marin, CA, who began his career in environmental medicine and now specializes in helping complex patients by searching for the root causes of their illness. He and Dr. Dempsey discuss their hypotheses about how and why some patients can get so sick, their favorite newer tests and treatments -- including g
Dr. Alexis Cutchins on venous compressions, POTS, MCAS, MALS and more
This is an excellent discussion for patients and practitioners alike who are interested in the connections between MCAS, POTS, venous compression, pelvic venous disorder, and MALS. Cardiologist Dr. Cutchins and Dr. Tania Dempsey share tons of information plus their latest thinking on how to treat patients with these complex presentations, including an
Women’s sexual health with Dr. Anna Cabeca
Dr. Anna Cabeca started her career as a researcher and busy physician, until her own fertility issues drove her to search the world over for better solutions for women's sexual health. In this interview with Dr. Dempsey we learn about hormones, symptoms, treatments, natural alternatives, that vaginal health is important for overall health, and much mor
MCAS in Developmental and Behavioral Pediatrics with Donna Kirchoff, MD, FAAP
Dr. Donna Kirchoff is an integrative developmental and behavioral pediatrician who works with children who have complex conditions, often involving MCAS, autism and other neuroinflammatory conditions like PANS and PANDAS. In this episode she and Dr. Dempsey discuss the role of mast cells in these conditions and what can be done to help these young pati
From Ayurveda to Apheresis with Gillian Ehrlich, DNP, ARNP
Gillian Ehrlich's NeuroVeda Clinic in Seattle treats complex patients with a wide variety of treatments including peptides, Ayurvedic medicine, diet and nutrition, imaging, mind-shifting therapeutics, plasmapheresis, and more. In this episode, Dr. Tania Dempsey interviews Gillian about her Ayurvedic approach and also her experiences with plasmapheresis
SIBO and gut health driving MCAS with Dr. Michael Ruscio
Dr. Ruscio is a thought leader, expert, clinician and researcher (and podcaster!) specializing in gut health and SIBO - small intestinal bacterial overgrowth. In this episode, he and Dr. Tania Dempsey discuss how gut health issues like SIBO can drive MCAS, plus Dr. Ruscio's approach to testing and treatment. This is a great conversation between top cl
Vibrant health starts with the heart - Master Coach Joseph Anew
Joseph Anew is now the picture of health and fitness, but as a young man he was severely injured and received a dior diagnosis. When conventional treatments failed, he moved to a tropical beach to live out his few remaining days. What happened next has been the basis for his great fitness and career helping others to overcome health challenges, feel th
Hormones and mast cells with Dr. Tania Dempsey
In this episode Dr. Dempsey explains how hormones can affect mast cells and vice verse, especially when it comes to puberty, menarche, pregnancy, and menopause.
More information about Dr. Tania Dempsey and her practice can be found at https://drtaniadempsey.com/.
If you liked this episode, we hope you will click subscribe so that you don't miss an ep
Michael Rubino on mold remediation, with Dr. Tania Dempsey
Michael Rubino is an air quality expert, environmental wellness advocate and President of Change the Air Foundation. He is widely known as the trusted source for mold remediation expertise. In this episode Dr. Dempsey and Michael discuss how to avoid mold in your environment, even if you don't have the means to move out of a moldy home.
Here is the mo
Dr. Dempsey on Mold/Mycotoxins and MCAS
Dr. Dempsey explains the facts on mold as a trigger for mast cells, including symptoms, preferred tests, treatments, resources for remediation and expectations for recovery. This is a not-to-be-missed episode since -- as we learn in this episode -- nearly everyone has likely had exposure to the types of mold that can be problematic. Dr. Dempsey is a m
Dr. Dempsey on infections (Q&A part 3)
In this 3rd Q&A session with the amazing Dr. Dempsey she goes deep on infections as a trigger for MCAS: How they're transmitted, symptoms, testing, treatment, and expectations for recovery. This is a not-to-be-missed episode since -- as we learn in this episode -- nearly everyone has likely had exposure to the types of infection that can be at pla
Dr. Jill Carnahan on her new book, film and approach to MCAS
This is a not-to-be-missed episode between two incredible physicians: Dr. Jill is a highly sought-after leader in functional medicine and a survivor of cancer/crohne's/MCAS. She and Dr. Dempsey compare approaches to treating MCAS, discuss Dr. Jill's new book and film, and describe some lesser-known treatment strategies like methylene blue with red ligh
Breast Implants and MCAS Insights with Surgeon Eva Nagy
Dr. Dempsey interviews breast surgeon Dr. Eva Nagy about her important new findings just published about evidence of mast cell activation in Breast Implant Illness. Dr. Nagy is the world's leading surgeon for explant surgery and previously covered Breast Implant illness in episode 184.
Dr. Nagy's website is here and her new publication is here.
Dr. Dem
More Dr. Dempsey answering listener questions (part 2)
Nobody answers your MCAS questions as rapid-fire as Dr. Dempsey! She's back to answer listener questions, addressing the topics of anaphylaxis, Epi-Pens, difficult blood draws, itching, what to do when otherwise healthy or important activities cause flares, and so much more.
More information about Dr. Tania Dempsey can be found at https://drtaniadempse
Underappreciated MCAS strategies with Dr. Kelly McCann
Dr. Kelly McCann is a leading educator on MCAS and related complex disease, with her online seminars and an approach that combines functional, integrative and environmental medicine. Drs Dempsey and McCann have a far-reaching conversation about MCAS strategies and factors ranging from mindset to muscle testing to genetic predisposition for breaking dow
Mold-induced Illness is Treatable with Dr. Neil Nathan
Dr. Neil Nathan is the leading expert on mold and mycotoxin illness, and in this episode he and Dr. Tania Dempsey discuss how mold can cause chronic illness and how to treat it. They also discuss Dr. Nathan's new book, The Sensitive Patient's Healing Guide, available here from Amazon. Dr. Nathan's other books and resources, plus information about work
Vote now to raise awareness and funds with (the very strong) Dr. Tania Dempsey
Dr. Tania Dempsey shares her passion (and some tips) for bodybuilding, because she has been nominated to be on the cover of Muscle and Fitness Hers magazine! If she is voted to be on the cover, it will raise awareness of complex conditions like POTS/MCAS/hypermobility spectrum disorder, AND Dr. Dempsey would donate the $20,000 prize to the documentary
Mast cells driving Dysautonomia (& much more) with Mast Cell Master Dr. Theoharides
Dr. Theoharides is among the world's top mast cell researchers and speaks with Dr. Dempsey about his recent article reviewing how mast cells may drive dysautonomia and vice verse. They also cover a range of topics from mast cells' diversity to their role in autism, most effective mast cell stabilizers and much more. This episode is packed with advance
Dr. Dempsey answers listener questions
Dr. Dempsey answers questions about MCAS and depression/anxiety/fatigue/brain fog; physical triggers; Kounis Syndrome; whether it's worth it to allow "small" flares in the name of pizza or other small joys; treatments such as stenting for venous compression; how long to try each antihistamine; and much more.
More information about Dr. Tania Dempsey can
Unraveling Complexity in Chronic Illness with Dr. David Kaufman
Dr. David Kaufman is renowned for working with the most complex patients and for his podcast on Patreon, Unraveled: Understanding Medical Complexity. He and Dr. Dempsey discuss the role of MCAS in ME/CFS and other complex disorders and how he starts unraveling these complex clusters of conditions. You can learn more about Dr. Kaufman and his practice
MCAS, POTS & Pediatric Cardiology with Dr. Jeffrey Boris
Dr. Dempsey interviews pediatric cardiologist Dr. Jeffrey Boris about the Triad (MCAS, POTS and hypermobility syndromes) in his pediatric population. As an avid researcher and data analyst, Dr. Boris is always a wealth of knowledge on latest findings and yet-unpublished trends and hypotheses. The doctors also exchange interesting observations about MC
Behind the Scenes of the Triad Documentary with the Producers/Doctors: A crossover episode
We have the entire medical/production team of 5 physician/researchers to give us an update and behind-the-scenes look at the documentary they are making about the trifecta of MCAS, dysautonomia/POTS, and hypermobility spectrum disorders. We hear from doctors Tania Dempsey, Larry Afrin, Linda Bluestein, Lawrence Kinsella and Leonard Weinstock, along wit
MCAS & Breast Implant Illness with Breast Surgeon Eva Nagy, MD
Dr. Dempsey interviews Dr. Eva Nagy, a world-renowned breast surgeon experienced in all sorts of breast surgeries, who has developed special interest and skill in treating breast implant illness (BII), which she believes can be related to mast cell activation syndrome (MCAS). Dr. Nagy describes BII, how she removes problem implants, and the effects thi
Psychiatric Manifestations of MCAS with Dr. Janet Settle
Dr. Settle is a psychiatrist who believes that mast cell activation is responsible for some symptoms of anxiety, depression, bipolar disorder type II and others. She treats MCAS as a way to stabilize both mast cells and their emotional state.
You can learn more about Dr. Settle and her practice here.
You can learn more about Dr. Dempsey and her practice
Mast Cells, Pain and Hypermobility with Dr. Linda Bluestein
MCAS expert Dr. Bluestein is an anesthesiologist and pain specialist focusing on hypermobility and its associated pain syndromes. Having EDS and her own pain, she discusses the use of opioids, ketamine, pain programs in this population, and much more!
You can learn more about Dr. Bluestein and her practice and podcast here.
You can learn more about Dr.
Documentary on The Triad with Dr. Leonard Weinstock
Dr. Weinstock and Dr. Dempsey are spearheading the creation of a documentary about MCAS, POTS, and EDS. Still in the planning stages, this documentary intends to educate medical professionals and the general public. We hope that it will help raise awareness!
Link to the LDN Research Trust:https://ldnresearchtrust.org/mast-cell-activation-syndrome-docume
Cardiac manifestations of MCAS with Dr. Andrew Maxwell
Treating MCAS, POTS, and Long COVID can be difficult, and physicians must attack from various angles to get patients feeling better. Dr. Maxwell walks us through his thinking and how MCAS is linked to POTS and Long COVID. This episode is a must-listen for patients and practitioners alike.
You can read the transcript for this episode here: http://tinyurl
GI Manifestations of MCAS with Dr. Leonard Weinstock
Dr. Weinstock, a gastroenterologist and leading expert on MCAS, discusses mast cells in the context of the GI tract. Bloating, gas, SIBO, SIFO, and IBS are all discussed in this episode. In addition, he shares how he prescribes LDN for his patients. There is a ton of great information in this episode for patients and practitioners alike!
You can read th
Dr. Lawrence Afrin on MCAS Diagnostic Criteria “Consensus-2”
Dr. Afrin, a world expert in all things mast cell, talks in depth about issues with the first MCAS "consensus" statement and the need for a second MCAS consensus statement so that patients can be treated even if their lab tests don't show an elevation of tryptase levels. This opens the diagnostic door to many additional patients so that they can get the
Diagnosis & Treatment of MCAS with Dr. Tania Dempsey
Dr. Dempsey shares her experience in both diagnosing and treating people with MCAS. She always looks for POTS and orthostatic symptoms during diagnosis, as these are often comorbid disorders. Antihistamines and other major medications commonly used to treat MCAS are also discussed.
You can learn more about Dr. Dempsey and her practice here.
You can read
Introduction to mast cells and mast cell activation syndrome (MCAS) with Dr. Tania Dempsey
Dr. Dempsey is helping us to launch a new series within the POTScast focusing on all things mast cells. These cells are an important part of the immune system and are found throughout the body. Learn more about what happens with these cells malfunction!
You can learn more about Dr. Dempsey and her practice here.
You can read the transcript for this ep
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