JAMAevidence Users' Guides to the Medical Literature
JAMA editors and authors explain the methods underlying clinical research to help students, trainees, and health professionals use the published medical literature to make evidence-based decisions for patients. JAMAevidence is an evidence-based medicine (EBM) resource created and maintained by the JAMA Network to promote the use of EBM to improve patient care.
Episodes
Understanding Bias and Random Error in Medical Research With Dr Furukawa
Toshi A Furukawa, MD, PhD, Kyoto University, Graduate School of Medicine, School of Public Health, discusses Understanding Bias and Random Error in Medical Research with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: CONSORT 2025 Statement Using Instrumental Variables to Address Bias From Unobserved Confounders
How to Use a Patient Management Recommendation: Clinical Practice Guidelines and Decision Analyses With Dr Agoritsas
Thomas Agoritsas, MD, PhD, Geneva University Hospitals, Switzerland discusses Users' Guides to the Medical Literature about patient management recommendations with author Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation Platelet Transfusion Caring for Patients With Acute Respiratory Distress Syndrome
Evidence-Based Practitioners and Evidence-Based Care With Dr Wilson
Mark C. Wilson, MD, MPH, University of Iowa, Carver College of Medicine discusses Evidence-Based Practitioners and Evidence-Based Care with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content:
Teachers' Guides to the Users' Guides
Mark C. Wilson MD, MPH, University of Iowa, discusses Teachers' Guides to the Users' Guides with Gordon H. Guyatt, MD, MSc, McMaster University. Related Content: Evidence vs Consensus in Clinical Practice Guidelines How to Interpret and Use a Clinical Practice Guideline or Recommendation
Assessing the Strength of Recommendations: The GRADE Approach With Dr Vandvik
Gordon H. Guyatt, MD, MSc, discusses Assessing the Strength of Recommendations: The GRADE Approach with Per Olav Vandvik, MD, PhD. Related Content: How to Interpret and Use a Clinical Practice Guideline or Recommendation
Understanding and Applying the Results of a Systematic Review With Dr Murad
Host Gordon Guyatt, MD, MSc, discusses Understanding and Applying the Results of a Systematic Review with M. Hassan Murad, MD, MPH. Related Content: How to Read a Systematic Review and Meta-analysis and Apply the Results to Patient Care Acute Treatments for Episodic Migraine in Adults
Fixed-Effects and Random-Effects Models With Dr Murad
Gordon H. Guyatt, MD, MSc, discusses Fixed-Effects and Random-Effects Models with M. Hassan Murad, MD. Related Content: Random-Effects Meta-analysis
Adjusted Analyses in Studies Addressing Therapy and Harm With Dr Agoritsas
Gordon H. Guyatt, MD, MSc, discusses Adjusted Analyses in Studies Addressing Therapy and Harm with Thomas Agoritsas, MD, PhD. Related Content: Adjusted Analyses in Studies Addressing Therapy and Harm
Spectrum Bias With Dr Reem A. Mustafa
Gordon Guyatt, MD, MSc, discusses Spectrum Bias with Reem A. Mustafa. MD, MPH, PhD.
Discrimination and Calibration of Clinical Prediction Models With Dr Alba
Gordon Guyatt, MD, MSc, discusses Discrimination and Calibration of Clinical Prediction Models with Ana Carolina Alba, MD, PhD. Related Content: Discrimination and Calibration of Clinical Prediction Models With Dr Alba Read Transcript
How to Interpret and Use a Clinical Practice Guideline or Recommendation With Dr Gordon Guyatt and Dr Brignardello-Petersen
Host Robert M. Golub, MD, discusses How to Interpret and Use a Clinical Practice Guideline or Recommendation with Gordon H. Guyatt, MD, MSc, and Romina Brignardello-Petersen, DDS, MSc, PhD.
Measuring Agreement Beyond Chance With Dr Thomas McGinn
Gordon Guyatt, MD, discusses Measuring Agreement Beyond Chance with Thomas McGinn, MD, MPH. Related Content: Does This Patient Have Infectious Mononucleosis? The Rational Clinical Examination Systematic Review
Correlation and Regression With Dr Jaeschke
Gordon H. Guyatt, MD, MSc, discusses
Economic Analysis With Dr Paul Moayyedi
Gordon Guyatt, MD, discusses economic analysis with Paul Moayyedi, PhD
Misleading Presentations of Clinical Trial Results with Dr Victor Montori
Gordon Guyatt, MD, discusses Misleading Presentations of Clinical Trial Results with Victor Montori, MD Related Content: Misleading Presentations of Clinical Trial Results with Dr Victor Montori When Can Intermediate Outcomes Be Used in Clinical Trials? When Guidelines Recommend Shared Decision-making
Surrogate Outcomes from the Users' Guides to the Medical Literature
Anne M. Holbrook, MD and Gordon Guyatt, MD, discuss Surrogate Outcomes from the JAMA Users' Guides to the Medical Literature Related Content: When Can Intermediate Outcomes Be Used as Surrogate Outcomes? FDA Acceptance of Surrogate End Points for Cancer Drug Approval: 1992-2019 What Constitutes a Valid Surrogate End Point in Cancer Clinical Trials?
How to Read Articles That Use Machine Learning With Yun Liu, PhD
Interview with Yun Liu, author of How to Read Articles That Use Machine Learning: Users' Guides to the Medical Literature
Cluster Randomized Trials: Evaluating Treatments Applied to Groups With William J. Meurer, MD
JAMA Deputy Editor Edward Livingston, MD, discusses "Cluster Randomized Trials: Evaluating Treatments Applied to Groups" With William J. Meurer, MD, MS
Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process with Dr Kert Viele
Ed Livingston, MD, FACS, AGAF, discusses Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process with Kert Viele, PhD
Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Dr Amy Kaji
Ed Livingston, MD, FACS, AGAF, discusses Noninferiority Trials: Is a New Treatment Almost as Effective as Another? with Amy Kaji, MD, PhD
Decision-making and the Patient with Dr Victor Montori
Gordon Guyatt, MD, MSc, discusses Decision-making and the Patient with Victor Montori, MD, MSc.
JAMA Guide to Statistics and Methods
Clinical researchers and biostatisticians use highly specialized language to help them discuss statistics and research methods efficiently. In 2019 JAMA published the JAMA Guide to Statistics and Methods, a book of short reviews that translate that specialized language and explain statistics and methods to a broad physician readership. The book's editors and authors, Edward Livingston, MD, and Rog
Applying Results to Individual Patients with Dr Thomas Agoritsas
Gordon Guyatt, MD, MSc, discusses the application of the results of systematic reviews and meta-analyses to individual patients with author Thomas Agoritsas, MD.
How to Use a Subgroup Analysis with Dr Gordon Guyatt
Dr Edward Livingston discusses How to Use a Subgroup Analysis with Dr Gordon Guyatt
Composite End Points With Dr Gordon Guyatt
Dr Ed Livingston discusses Composite End Points with Gordon Guyatt
Differential Diagnosis With Dr Scott Richardson
Dr Gordon Guyatt discusses Differential Diagnosis with Scott Richardson
How to Use an Article About Genetic Association With Dr John Attia
Dr Gordon Guyatt discusses How to Use an Article About Genetic Association with Dr John Attia
How to Use an Article About Hypothesis Testing and Appropriate Interpretation of P Values: Interview With Dr George Tomlinson
Demetrios N. Kyriacou discusses How to Use an Article About Hypothesis Testing and Appropriate Interpretation of P Values with Dr George Tomlinson
Obstructive Sleep Apnea: Interview With Dr Kathryn A. Myers
Dr David Simel discusses Obstructive Sleep Apnea with Dr Kathryn A. Myers.
How to Use an Article About Quality Improvement: Interview With Dr Eddy Fan
Dr Demetrios Kyriacou discusses How to Use an Article About Quality Improvement with Dr Eddy Fan.
Network Meta-analysis: Interview With Dr Gordon Guyatt
Dr Demetrios Kyriacou discusses Network Meta-analysis with Dr Gordon Guyatt.
The Principle of Intention to Treat and Ambiguous Dropouts: Interview With Dr Matthias Briel
Dr Amy Thompson discusses the Principle of Intention to Treat and Ambiguous Dropouts with Dr Matthias Briel.
Evidence-Based Medicine and the Theory of Knowledge: Interview With Dr Gordon Guyatt
Dr Amy Thompson discusses Evidence-Based Medicine and the Theory of Knowledge with Dr Gordon Guyatt.
Clinical Prediction Rules: Interview With Dr Thomas G. McGinn
Dr Ed Livingston discusses Clinical Prediction Rules with Dr Thomas G. McGinn.
Recommendations About Screening: Interview With Gemma Louise Jacklyn
Dr Ed Livingston discusses Recommendations About Screening with Gemma Louise Jacklyn.
How to Use a Noniferiority Trial: Interview With Dr Gordon Guyatt
Dr Ed Livingston discusses How to Use a Noniferiority Trial with Dr Gordon Guyatt.
The Process of a Systematic Review and Meta-analysis: Interview With Dr M. Hassan Murad
Dr Ed Livingston discusses Systematic Review and Meta-analysis with Dr M. Hassan Murad.
Understanding the Results: More About Odds Ratios: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses Understanding the Results: More About Odds Ratios with Dr Gordon Guyatt.
Why Study Results Mislead: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses Why Study Results Mislead with Dr Gordon Guyatt.
Surprising Results of Randomized Trials: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses Surprising Results of Randomized Trials with Dr Gordon Guyatt.
Diagnostic Tests: Interview With Dr Toshi A. Furukawa
Joan Stephenson, PhD, discusses Diagnostic Tests with Dr Toshi A. Furukawa.
Confidence Intervals: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses Confidence Intervals with Dr Gordon Guyatt.
Prognosis: Interview With Dr Adrienne Randolph
Joan Stephenson, PhD, discusses Prognosis with Dr Adrienne Randolph.
Philosophy of Evidence-Based Medicine: Interview With Dr Victor Montori
Joan Stephenson, PhD, discusses Philosophy of Evidence-Based Medicine with Dr Victor Montori.
Harm (Observational Studies): Interview With Dr Mitchell Levine
Joan Stephenson, PhD, discusses Harm (Observational Studies) with Dr Mitchell Levine.
Does Treatment Lower Risk?: Interview With Dr Roman Jaeschke
Joan Stephenson, PhD, discusses Does Treatment Lower Risk?: Interview with Dr Roman Jaeschke.
Measuring Patients' Experience: Interview With Dr Toshi A. Furukawa
Joan Stephenson, PhD, discusses Measuring Patients' Experience with Dr Toshi A. Furukawa.
N-of-1 Randomized Controlled Trials: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses N-of-1 Randomized Controlled Trials with Dr Gordon Guyatt.
Randomized Trials Stopped Early for Benefit: Interview With Dr Victor Montori
Joan Stephenson, PhD, discusses Randomized Trials Stopped Early for Benefit with Dr Victor Montori.
Finding the Evidence: Interview With Dr Ann McKibbon
Joan Stephenson, PhD, discusses Finding the Evidence with Dr Ann McKibbon.
Summarizing the Evidence: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses Summarizing the Evidence with Dr Gordon Guyatt.
The Process of Diagnosis: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses The Process of Diagnosis with Dr Gordon Guyatt.
Therapy (Randomized Trials): Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses Therapy (Randomized Trials) with Dr Gordon Guyatt.
What Is the Question? Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses What Is the Question? with Dr Gordon Guyatt.
The 5As of the Health Information Cycle: Interview with Dr Robert Hayward
Joan Stephenson, PhD, discusses The 5As of the Health Information Cycle with Dr Robert Hayward.
Applying Evidence-Based Practice: Interview With Dr Robert Hayward
Joan Stephenson, PhD, discusses Applying Evidence-Based Practice with Dr Robert Hayward.
The Origin of Evidence-Based Medicine and the Users' Guides to the Medical Literature: Interview With Dr Gordon Guyatt
Joan Stephenson, PhD, discusses The Origin of Evidence-Based Medicine and the Users' Guides to the Medical Literature with Dr Gordon Guyatt.
Introduction to JAMAevidence: the Fundamental Tools for Dealing With the Medical Literature and Making Clinical Diagnoses
Dr Drummond Rennie discusses Introduction to JAMAevidence: the Fundamental Tools for Dealing With the Medical Literature and Making Clinical Diagnoses.
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