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Plenary Session

Vinay Prasad, MD MPH 402 Episodes Sep 7, 2026

A podcast about medicine, oncology, and health policy. Hosted by Vinay Prasad, MD MPH from the University of California, San Francisco. The show invites listeners to share feedback on Twitter or via email.

Episodes

5.05 Measles in PA, Nature's editorial, and more Sep 7, 2026 00:22:50 5.05 Measles in PA, Nature's editorial, and more by Plenary Session

5.04 Jason Arday, Nathan Cofnas and the Decline of University Standards Aug 26, 2026 00:30:28 5.04 Jason Arday, Nathan Cofnas and the Decline of University Standards by Plenary Session

5.03 - 5 red flags, Betting Markets, Covid Czar says lab origin Aug 7, 2026 00:25:40 5.03 - 5 red flags, Betting Markets, Covid Czar says lab origin by Plenary Session

Season 5 Ep 2 - Anthony Fauci's Diary and Congressional Testimony Aug 4, 2026 00:21:15 Season 5 Ep 2 - Anthony Fauci's Diary and Congressional Testimony by Plenary Session

Reboot - I am back with Audio podcasts Jul 21, 2026 00:51:48 Reboot - I am back with Audio podcasts by Plenary Session

Longevity Episode 2 - Nutrition science May 20, 2026 00:36:52 Longevity Episode 2 - Nutrition science by Plenary Session

Longevity Lecture series Introduction and Lecture 1 May 12, 2026 00:29:23 Longevity Lecture series Introduction and Lecture 1 by Plenary Session

CABINET - trial - Cabozantinib for NET Feb 20, 2025 00:19:17 Back to basics as I break down a trial

RFK Jr takes office/ CDC layoffs/ Varmus criticizes Jay's proposal for Academic Freedom Feb 19, 2025 00:27:39 I discuss RFK Jr.'s confirmation as the US Secretary of Health and Human Services; recent layoffs at the CDC and NIH; and some comments by Harold Varmus in criticism of Jay Bhattacharya.

Trump is breaking media brains / NIH cuts indirect payments and scientists freak out Feb 19, 2025 00:27:17 I discuss the intense media coverage of Trump and the recent decision to cap indirect costs of NIH grants at 15%.

Elon's 6 Engineers/ Unelected/ RFK Jr/ MMR vaccines/ DEI/ USAID and NIH funding complaints Feb 19, 2025 00:22:54 I'm talking about USAID and Elon's team of six engineers; the Bobby Kennedy Jr hearings, particularly concerning Samoa; MMR vaccines; DEI; and NIH funding complaints.

Why the NIH is a broken funding system Feb 19, 2025 00:31:48 I discuss the recent reduction in indirect funds for NIH grants and lay out why the NIH is a broken funding system.

CIA says lab leak, Fauci's pardon, NIH's meetings, RFK Jr's hearing & more! Feb 19, 2025 00:38:48 I discuss the CIA admitting that COVID was a lab leak; Fauci's pardon; NIH meetings; RFK Jr's Senate confirmation hearing; and more.

Trump's Big Health Care Changes: NIH study sections, MMWR gag order, WHO withdrawal & more! Feb 1, 2025 00:29:11 I discuss Trump's big health care changes: NIH study sections, the MMWR gag order, the US withdrawal from WHO, and more!

The ENTIRE healthcare system is broken, not just health insurance companies Jan 27, 2025 00:18:51 The entire healthcare system is broken, it's not just health insurance companies.

Alcohol - Is it healthy? Everything you need to know about Beer, Wine and Spirits Jan 24, 2025 00:41:27 Is alcohol healthy for you? I break down everything you need to know about beer, wine, and spirits.

2 HOUR ASH Presentation with AARON GOODMAN & MANNI & More Dec 11, 2024 01:58:16 Our 2 hour critical appraisal and ASH review. SO many guest stars

Systematic Reviews - An Introduction⧸ How to do them⧸ Search Strategies⧸ Common Errors Nov 13, 2024 00:48:40 Lecture on systematic review, given by Vinay Prasad MD MPH to students in the UCSF Training in Clinical Research Program, November 2024.

Special post-ESMO 2024 edition ! Nov 3, 2024 00:31:04 Timothee Olivier and I discuss the top ESMO 2024 abstracts!

Artificial Intelligence in Medicine - My Keynote Oct 28, 2024 00:59:03 AI in healthcare - my latest keynote address

Masking Mistakes - my panel discussion at the Emory Center for Ethics Oct 16, 2024 01:36:47 "Masking Mistakes: Lessons from the Science, Policy, and Coverage of COVID-19", the 2024 Brian Shields Lecture on Institutional Ethics which took place on Monday, October 7, 2024 for the Emory Center for Ethics. A conversation with Carlos Del Rio, MD and Vinay Prasad, MD MPH with moderation by Gerard Vong, DPhil, Director of the MA in Bioethics program.

How We Can Do Better As A County Hospital Aug 31, 2024 00:41:34 Screening/ Drug efficacy/ Sotorasib/ Adaura and more

Driver mutation lung cancer - My lecture Aug 2, 2024 00:37:22 My UCSF lecture on driver mutation lung cancer

Post ASCO wrap up with Timothee Olivier Jun 23, 2024 00:45:27 We break down the best studies from ASCO

Critical Appraisal - My 2 hour ASCO lecture - Day 2 version Jun 5, 2024 01:54:09 Critical Appraisal - My 2 hour ASCO lecture - Day 2 version by Plenary Session

Asco Prequel - We talk about what to look for May 30, 2024 00:29:34 What you need to know in advance of ASCO

A SM crossover - Cifu, Prasad, Mandrola May 27, 2024 00:45:22 Should trials have carbon footprint as an endpoint?

When Evidence EXPIRES - My Grand Rounds Today at Mt Sinai May 17, 2024 00:52:42 My grand rounds; Beta blockers post MI Single center vs multicenter RCT Masks Boosters and more

Cifu, Mandrola, Prasad - SM crossover May 10, 2024 00:41:50 I crossover SM podcast; Harvard med students video, Justice curriculum, Masking half the year

Patient advocates funded by Pharma Apr 17, 2024 00:26:14 Patient advocates, Pharma funding, and is MRD a suitable endpoint

FDA makes MRD the basis for AA Apr 12, 2024 00:08:32 5 reasons that is a bad idea

Beta Blockers After Heart Attacks Don't Work Apr 9, 2024 00:15:33 Another flawed quality metric. Reviewing the NEJM paper "Beta-Blockers After Myocardial Infarction and Preserved Ejection Fraction".

Blood based and Stool DNA colon cancer screening - Two NEJM papers Mar 27, 2024 00:26:06 They are shitty

Keynote 564 - a flawed study Feb 1, 2024 00:17:56 Another flawed study Keynote 564. Pembro in adjuvant RCC

CONTACT-01 Cabo/ Atezo in Prostate Cancer - An Unethical trial Jan 27, 2024 00:24:46 What happens when doctors run unethical studies?

CAR T causes MDS??? Manni, Goodman, Raj, Prasad Dec 28, 2023 00:27:27 Does car T cause secondary AML? We discuss

Timothee and Prasad talk 2023 cancer trials Dec 24, 2023 00:44:08 We talk about 2023 cancer trials

Aaron Goodman Prasad ASH UPDATES Dec 20, 2023 00:52:49 Goodman and I discuss ash updates. My myeloma talk https://www.youtube.com/watch?v=jAz84yCnfjQ

Mandrola and Prasad Dec 17, 2023 00:49:42 Subscribe to Sensible Med Pod; This is x over Post partum depression, orbita 2 and physics vs medicine

COVID19 Policy: What the US Got Wrong Nov 26, 2023 01:27:36 My Lecture in Curacao 4/4 Vaccines, Masks, Mandates, Lockdowns, School closure Other lectures to come

Lecture 1 of 4 Curacao - How to Keep Up with Literature Nov 24, 2023 00:41:32 Entresto, Lung Transplants, How to Keep Up with Literature - Lecture to Trainees in Curacao

Advice Pre-Med Students | Lecture at UC Berkeley Nov 11, 2023 00:48:19 This is a lecture I gave on November 5, 2023, to pre-medicine undergraduate students at University of California Berkeley.

Radiation oncology in GI malignancy - Nina Sanford and Bill Hall Oct 31, 2023 00:23:34 Radiation oncology in GI malignancy (endpoints and stratification) in the JCO

Hawai Keynote - Coffee and colon cancer & Censoring & More Oct 23, 2023 00:45:35 Prasad is back in Hawaii to give another keynote (good thing they cancelled Dallas not Honolulu). I discuss coffee and colon cancer, and censoring, and Lu177 PSMA

Ethics: How IRBs Can Do Better | My Denmark Lectures (Sept 2023) 3 Of 3 Oct 19, 2023 00:42:44 This is a lecture I gave on ethics and institutional review boards in Denmark in September 2023. It is the last of the three lectures I gave.

Prasad's lecture gets cancelled/ Cifu Gets COVID a SM crossover Oct 16, 2023 00:54:55 Mandrola, Prasad and Cifu are back to discuss the latest drama

The State Of Immunotherapy In Oncology | My Denmark Lectures (Sept 2023) 2 Of 3 Oct 9, 2023 00:46:04 This is a lecture I gave on the state of immunotherapy in oncology at the Immunotherapy Symposium In Denmark in September 2023. It is the second of three lectures I gave.

Do We Have Good Evidence For New Drugs? My Denmark Lectures (Sept 2023) 1 Of 3 Oct 4, 2023 01:16:08 The first of the three lectures I gave in Denmark in September 2023 was on the medical evidence behind decision-making by health technology assessment groups.

Great And Crazy Things We Do In Medicine Sep 20, 2023 01:54:47 This is the live recording of a talk given on the great and crazy things we do in medicine, from cancer drugs to boosters and more.

Fixing Cancer Medicine w/ Timothee Olivier Sep 12, 2023 00:42:59 Timothee is back to discuss Malignant and Solutions

Coumadin, ECMO, RCTs and more Sep 11, 2023 00:48:38 A far reaching discussion btw Mandrola and Prasad on RCTs, Coumadin, ECMO and RCTs for covid shots

Prasad and Mandrola discuss recent journal articles/ Republicans/ Stenting Aug 23, 2023 00:42:44 Simultaneously released on Sensible Medicine. Time to subscribe to Sensible Medicine substack and podcast.

Placebo/ Journal Errors/ Cancer Screening w/ Mandrola - SM crossover Jul 10, 2023 01:23:11 Placebo/ Journal Errors/ Cancer Screening w/ Mandrola - SM crossover

Testosterone/ Should Scientists Debate/ Mike Joyner Jun 28, 2023 00:59:19 A sensible medicine crossover episode Follow the sensible medicine podcast feed for more of these discussions

Post Protocol Therapy - QOL - Adjuvant - Olivier Joins VP Jun 10, 2023 00:41:22 T. Olivier from Geneva is back. A fan favorite guest. We discuss 3 recent papers.

ADAURA OS RESULTS - THE TRIAL WAS UNETHICAL Jun 8, 2023 00:24:07 Researchers were too busy counting dead bodies to give the control arm appropriate therapy when their cancer recurred. Disgusting conduct. I break down ADAURA

OBS studies vs RCTs - Trial Emulation - RCT Duplicate - We debate recent JAMA Paper May 17, 2023 01:15:06 Mike Putman, Todd C. Lee, John Mandrola and I debate the recent JAMA paper on RCT Duplicate. This is a spirited round table discussion on the limitations of observational data. If you are reading this, leave a comment as a review!

Myeloma Roundtable - Manni M. Raj C. VP discuss controversies May 13, 2023 01:20:55 Early treatment of myeloma, dual vs. single maintenance, and finally transplant or no transplant.

Mammographic Screening : A complete review of the evidence May 11, 2023 00:37:04 Why the USPSTF is wrong

The Crushing, Cruel Cost of Cancer Drugs - My Lecture Apr 29, 2023 00:30:37 Cost of Cancer drugs - VP's lecture

Sensible Med Crossover - Cifu/ Mandrola/ Prasad & Wallensky Apr 24, 2023 01:23:39 I combine two latest tracks on interpreting medical studies, medical boards, 7 doses of vaccine, and finally Walensky. Stay tuned.

Cochrane Mask Debates - Jefferson/ Heneghan/ Prasad Apr 15, 2023 01:17:52 We explore the fight btw NYTimes, Cochrane, and the last people keeping EBM alive

Zeb Jamrozik - Vaccine errors/ Sweden/ Equipoise & Science itself Apr 12, 2023 01:13:04 Zeb joins me for the 7th time to discuss all the key pandemic questions

Harvard-MIT Center for Reg. Science Lecture (4-4-23) - Dubious FDA drug Approvals Apr 5, 2023 00:57:38 My lecture to Harvard regulatory science

5.47 - Real World Evidence - Keynote Lecture in Denmark Mar 26, 2023 00:48:52 VP goes to Denmark to give the keynote at the Danish medical association conference

5.46 - What is Science: reflections on the field Mar 10, 2023 00:29:40 What is science?

5.45 - Bar Karmma - Karmma 3 | Idacel vs 'standard care Mar 7, 2023 01:52:18 Karmma 3 discussion; then Sensible Medicine on Long COVID, 4th year fellowships and more; Then my breakdown of FDA's NEJM Letter to the Editor

More basics on randomized controlled trials - Part 2 Mar 2, 2023 00:42:41 I get into endpoints, surrogates, validation, blinding, crossover, and control arms.

RCT 101 And Papa Heme Feb 28, 2023 01:10:25 I talk RCTs 101; KM Plots; Blinding: 2:1 randomization: Concealment and more. Then Papa Heme Tells you How to Find your First Job

Tom Newman And VP Discuss Public Health Feb 22, 2023 00:56:48 Dr. Tom Newman UCSF Emeritus Professor & Superb teacher discusses VP's recent Public Health Videos. The two don't fully agree, but the discussion is worth your time.

5.41 - Michael Putman MCW debates me on recent policy Qs Feb 16, 2023 01:07:24 Mike Putman, asst prof. EBM Rhematologist debates me on value of boosters, observational studies and more.

Sensible Med Superbowl Plenary Session Crossover Feb 13, 2023 00:53:41 A new podcast feed called Sensible Medicine is up; here is a sample of what we have to offer

5.39 - Sotorasib and Codebreak 200 Feb 10, 2023 00:44:56 I destroy the trial. Bad control arm. Informative Censoring. No OS gain. Authors DOWNPOWERED TRIAL. Fishy PFS. Fishy HRQoL. This trial should be in trash can.

Myeloma Twitter Just Makes Things Up - Lessons for All Oncologists & Expertise Jan 22, 2023 00:42:08 I annotate an online case discussion; Every decision is not based in evidence. Madness

5.37 - Keynote Lecture on Physician Burnout Jan 15, 2023 00:40:10 This lecture on Burnout will not be like any other you have heard

5.36 - ASH UPDATE #4 - GEM CESAR Dec 30, 2022 00:22:02 I break down the GEM CESAR trial K, R, D, Pom, Dara, Dex, R, and Auto and all before you actually have cancer What a crazy trial!

5.35 - ASH Update #3 - the Ascent Trial Dec 29, 2022 00:19:14 This uncontrolled trial of Dara-KRD claims to be looking for cure; Unfortunately, the PI has not thought through what that would look like, and accordingly all the claims are incorrect. Moreover the primary endpt is negative. Sad day for oncology

5.34 - ASH Update #2 - ALPINE - Zanibrutinib vs Ibrutinib - Deconstructed Dec 24, 2022 00:21:37 Sample size games, primary endpoint, head to head trials in oncology Rate this podcast on itunes Coming next is Triangle trial

5.33 USC Grand Rounds Hematology Dec 23, 2022 00:47:59 Grand rounds on heme and heme malignancies given 12/16 at University of Southern California (some parts removed) More ASH coming soon

5.32 - ASH Update #1 - Talquetamab NEJM Dec 11, 2022 00:17:48 Is it acceptable to take someone with myeloma who has gotten just 2 regimens and put them on a phase 1? VP says hell no.

Plenary Session

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