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Practical AI in Healthcare

Practical AI in Healthcare

Steven Labkoff, MD and Leon Rozenblit, JD, PhD 45 Episodes Oct 11, 2026

AI promises to transform healthcare—but real, scalable impact remains rare. Practical AI in Healthcare cuts through the noise to showcase real-world use cases delivering business value today. Hosted by senior leaders—former VPs of life science technology groups, clinical informatics professionals from top-tier organizations, and a former Big Four consultant—each episode features candid conversations with the people making AI work inside the healthcare enterprise.

Episodes

Latha Valluripalli Soorya & Erica Crawford: Smart Glasses in Autism Evaluation
Latha Valluripalli Soorya & Erica Crawford: Smart Glasses in Autism Evaluation Oct 11, 2026 00:51:17 Families who suspect autism can wait up to two years for an evaluation. Dr. Latha Valluripalli Soorya, a clinical psychologist at Rush University Medical Center and co-founder of Argus Cognitive, and Dr. Erica Crawford, Clinical Director at Autism Testing 4 Kids in Dallas–Fort Worth, join Steve Labkoff and Leon Rozenblit to discuss Neurora: smart glasses a clinician wears during a standard autism
Sir Peter Donnelly of Genomics: Genetics as Nature's Drug Trial
Sir Peter Donnelly of Genomics: Genetics as Nature's Drug Trial Oct 4, 2026 00:55:07 Ninety-five percent of drug targets fail, and Professor Sir Peter Donnelly thinks the reason is simple: we can't run experiments on humans. Genetics is the next best thing. People who carry natural variants in a gene show what happens when that gene is dialed up or down over a lifetime. Peter, CEO and co-founder of Genomics, joins Steve Labkoff and Leon Rozenblit to explain how his company harmoni
Travis Zack: How OpenEvidence Picks and Grades the Evidence
Travis Zack: How OpenEvidence Picks and Grades the Evidence Sep 27, 2026 00:55:11 Doctors hallucinate too. That's the provocation Travis Zack, MD, PhD, chief medical officer of OpenEvidence, brings to this conversation with Steve Labkoff and Leon Rozenblit. A physician with 20 patients and no time to look things up goes with their gut, and can get it wrong in the same ways a language model does. Travis explains why OpenEvidence was built on retrieving evidence rather than gener
Randi Seigel & Jared Augenstein: Healthcare AI Law
Randi Seigel & Jared Augenstein: Healthcare AI Law Sep 20, 2026 00:54:15 By Manatt’s count, more than 280 bills to regulate AI in healthcare were introduced in 2026, and almost none of the resulting law has been tested in court. Randi Seigel, a partner at Manatt who leads its health care regulatory practice, and Jared Augenstein, a senior managing director at Manatt Health, track every one of them. They join Steve Labkoff and Leon Rozenblit to map where the states are
Greg Raiz: Data-Driven Early-Stage Investing
Greg Raiz: Data-Driven Early-Stage Investing Sep 13, 2026 00:55:28 Early-stage investing is one of the last places where big decisions get made on gut feel. Greg Raiz, co-founder and general partner of the pre-seed fund Founders Edge, is trying to change that with data: a survey of more than 3,000 entrepreneurs and a review of some 42 published studies on what predicts founder success. In a solo conversation with Leon Rozenblit, Greg explains why venture capital
Raihan Faroqui, MD: The Doctor at the Front Desk, AI on the Line
Raihan Faroqui, MD: The Doctor at the Front Desk, AI on the Line Sep 6, 2026 00:49:18 Raihan Faroqui trained in internal medicine and then went to work on the front desk. As VP of partnerships at Confido Health, he puts AI agents on the phone lines of what he says are about 1,500 outpatient practice sites, handling appointments, refills, insurance checks, and billing questions in twenty languages. His framing is that healthcare never had a software problem so much as a system of re
S1, E50 - Jeremy Harper: The Broken Adoption Curve, Ambient Scribes Nobody Can Audit, and the Knowledge We Keep Paying For and Deleting
S1, E50 - Jeremy Harper: The Broken Adoption Curve, Ambient Scribes Nobody Can Audit, and the Knowledge We Keep Paying For and Deleting Sep 2, 2026 00:53:04 Every technology healthcare has adopted moved through the same curve: a bleeding-edge few went first and documented what broke, and the majority followed. Large language models skipped that entirely. Jeremy Harper, a biomedical informatician who has worked at Epic, Ohio State, and Regenstrief, and who wrote Large Language Models (LLMs) for Healthcare, explains what we gave up by going all at once.
S1, E52 - Reflections #8: Year in Review
S1, E52 - Reflections #8: Year in Review Aug 30, 2026 00:48:09 Steve and Leon close Season 1 by looking back across all fifty-two episodes. They start with what surprised them (how fast conservative institutions adopted, and how slowly AI literacy is moving), then work through five conclusions a year of guests kept reaching independently: the models are no longer the hard part, almost nobody monitors these systems after deployment, an interface built for a no
S1, E51 - Reflections #7: When the Machine Is Almost Always Right, Who Is Still Thinking?
S1, E51 - Reflections #7: When the Machine Is Almost Always Right, Who Is Still Thinking? Aug 23, 2026 00:56:19 In their seventh Reflections episode, and their fifty-first overall, Steve and Leon look back across six conversations: Mika Newton on interoperability that finally started working, Peter Embi on monitoring clinical AI after deployment, Vimla Patel on how clinicians actually reason, Renee Deehan on an engine built so it can't hallucinate, Christine Dymek on AI literacy, and Jeremy Harper on an
S1, E49 - Chris Dymek: Healthcare AI Literacy
S1, E49 - Chris Dymek: Healthcare AI Literacy Aug 9, 2026 00:50:06 Chris Dymek came to healthcare informatics by way of philosophy, and she still thinks like a philosopher: the first question is what we actually mean. As Director of Digital Healthcare Research at AHRQ, she funded AI research, helped launch work on AI and patient safety, and wrote a request for information asking healthcare organizations how they thought about AI literacy. It was never published.
S1, E48 - Renee Deehan: Trustworthy AI for Consumer Health
S1, E48 - Renee Deehan: Trustworthy AI for Consumer Health Aug 2, 2026 00:50:44 The internet is full of wellness advice built on a single cherry-picked study. Renee Deehan, a molecular and cell biologist who leads science and AI at InsideTracker, spent two decades building the opposite. In this episode, she explains why the core of their recommendation engine is symbolic AI, knowledge representation and reasoning, rather than a large language model: it's deterministic, fu
S1, E47 - Vimla Patel: Cognitive Science of Clinical Reasoning
S1, E47 - Vimla Patel: Cognitive Science of Clinical Reasoning Jul 26, 2026 00:54:05 Dr. Vimla Patel has spent four decades studying how physicians actually reason, and what happens when technology ignores it. In this episode, she explains the difference between forward reasoning (the fast, pattern-driven hallmark of expertise) and backward reasoning (the slower, hypothesis-testing mode of novices), and why most clinical AI is built for the wrong one. Through two vivid cases, a te

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