JAMA+ AI Conversations
JAMA+ AI Conversations is a podcast from the JAMA Network that explores how artificial intelligence is reshaping medicine. Each episode features interviews with clinicians, researchers, and AI experts discussing real-world applications of AI in clinical practice, medical training, and research. The show examines both the opportunities and the challenges at the intersection of AI and health care. Listeners get insight into emerging tools and what the future of AI-driven medicine may look like.
Episodes
Will Women Physicians Face an AI Gap?
In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Rochelle Walensky, MD, MPH, professor of medicine at Harvard Medical School and former CDC Director, discuss the potential for AI deployment in health care to adversely impact women physicians, and why simply avoiding these technologies is not a realistic response. Related Content: Will Women Physicians Face an AI Gap? Women, Me
Beyond the AI Alarm: How ARPA-H Is Rethinking Innovation in Health Care
Yulin Hswen, ScD, MPH, Associate Editor of JAMA+ AI, speaks with Advanced Research Projects Agency for Health (ARPA-H) Program Manager Bon Ku, MD, MPP, about rethinking AI in health care from alarm fatigue and aviation-style simulation to patient-centered design and what it will take to safely move AI from promising models to real-world care. Related Content: Beyond the AI Alarm Related Link:
From Aging to AI and Beyond: A Conversation With Eric Topol
In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Eric Topol, MD, move from the science of aging to how to think about AI-enabled medicine. Topol discusses what it will take for AI to move medicine from reactive to predictive, why some well-validated imaging AI remains underused while large language models have spread rapidly, and whether AI is actually giving clinicians more tim
ADVOCATing for Patients With Heart Failure
In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Haider Warraich, MD, sort out the prospects for AI-driven heart failure care that doesn't entail a human in the loop. Warraich is a program manager at ARPA-H, the Advanced Research Projects Agency for Health, responsible for ADVOCATE, an effort to support the development of AI to guide heart failure treatment, seeking to create AI
Enriching Clinical Trials With Machine Learning
In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Joseph Geraci, PhD, of Queen's University discuss using machine learning to analyze clinical trials and related FDA interactions. Geraci's work focuses on identifying subpopulations with different responses to help plan and analyze future trials. Related Content: Enriching Clinical Trials With Machine Learning
From the JAMA Network: Acoustic Analysis of Primary Care Patient–Clinician Conversations to Screen for Cognitive Impairment
Interview with Joseph T. Colonel, PhD, author Acoustic Analysis of Primary Care Patient–Clinician Conversations to Screen for Cognitive Impairment. Hosted by Cynthia E. Armand, MD. Related Content: Acoustic Analysis of Primary Care Patient–Clinician Conversations to Screen for Cognitive Impairment
From the JAMA Network: AI Scribes Are Here, but Is Health Care Ready?
The rise in use and function of ambient AI scribes is arguably one of the fastest technologic changes ever seen in health care. In this episode of Healthy Dialogue, host Derek Angus, MD, MPH, is joined by Vincent Liu, MD, MS, Chief Data Officer of The Permanente Medical Group in Kaiser Permanente, to discuss the rapidly changing world of ambient AI. Related Content: Ambient AI Scribes and the Qu
From Silicon Valley to the Vatican: The Expanding Debate on AI Ethics
In this episode of JAMA+ AI Conversations, Roy Perlis, MD, MSc, and Yulin Hswen, ScD, MPH, discuss Anthropic's participation in the Vatican presentation of Pope Leo XIV's AI encyclical, Magnifica Humanitas. The conversation explores AI ethics, interpretability, governance, AI safety, and the growing role of health care, public health, and global institutions in shaping the future of AI. Related C
The Wizard of Oz in Medical AI
Is it enough for AI to be accurate, or are we mistaking performance for impact? Does AI change clinician behavior, improve patient decisions, or simply create a convincing performance of intelligence? Yun Liu, PhD, research scientist at Google Research, speaks with JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, about what is behind the curtain in these AI systems. Related Content: The Wizard o
Teaching AI to Read Patient Histories
Every patient has a story, but in modern health care that story is buried across thousands of notes, lab results, and fragmented records. Nigam H. Shah, MBBS, PhD, of Stanford University Department of Medicine joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to explore how researchers are building AI systems that can read and understand a patient's full medical history in seconds. Related Conte
Designing Trustworthy Clinical AI
Join JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, for a conversation about the practical implementation of trustworthy clinical AI. Guests Emily Tat, MD, and Peter Brodeur, MD, discuss ARISE, a research network focused on the real-world effects of AI on clinical care. Related Content: Designing Trustworthy Clinical AI
AI at the Policy Table
As artificial intelligence increasingly shapes population health decisions, evidence and accuracy matter. In this episode of JAMA+ AI Conversations, Associate Editor Yulin Hswen, ScD, MPH, speaks with Sandro Galea, MD, MPH, DrPH, Editor of JAMA Health Forum, about how AI is entering health policy, when it is ready for use, and what rigorous, policy-focused AI research is most needed. Related Cont
AI Drug Safety in Pregnancy
Why can signals that appear consistent across many studies still reflect shared bias; how do sibling comparisons help recalibrate cumulative evidence; and what AI-enabled approaches can add to large-scale evidence integration? Viktor H. Ahlqvist, PhD, from the Karolinska Institute joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss why automated drug safety surveillance duri
Understanding Disease Trajectories With AI
How might AI amplify epidemiological insight into neurodegenerative and systemic disease? JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, speaks with Fang Fang, MD, PhD, professor at Karolinska Institutet and head of the Integrative Epidemiology group. Drawing on Fang Fang's work in ALS, Parkinson disease, dementia, energy metabolism, immune modulation, and gut microbiome interactions, their conv
AI Chatbots and Youth Mental Health
What are the safety, evidence standards, and transparency needed for AI chatbots used in mental health contexts, particularly for young people. John Torous, MD, MBI, JAMA Psychiatry Author Interviews podcast host, joins JAMA+ AI Associate Editor Yulin Hswen, ScD, to discuss risks, data protections, and the clinical safeguards required to ensure responsible use. Related Content: AI Chatbots and Y
Leaping Forward Into… What? An Interview With Dr Robert Wachter
Dr Robert Wachter, chair of the Department of Medicine at UC San Francisco, speaks with JAMA+ AI Editor in Chief Roy Perlis about his new book, "A Giant Leap." Their discussion addresses multiple potential impacts of AI in medicine in terms of clinical practice but also training the next generation of clinicians. Related Content: Leaping Forward Into…What?—An Interview With Robert M. Wachter
AI and "Do No Harm"
In this episode, JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, speaks with David Wu, MD, PhD, and Adam Rodman, MD, MPH, about what safe clinical use of LLMs requires. Drawing on the framework of Do No Harm, they examine failure modes, limits of accuracy-based evaluation, clinician AI interaction, and safeguards needed as medical AI moves into patient care. Related Content: From AI Bench to AI
Stumbling Toward AI in the Clinic
In this episode of JAMA+ AI Conversations, Editor in Chief Roy Perlis and Associate Editor Yulin Hswen debate recent articles highlighted in JAMA+ AI, including work on patient messaging and suicide screening, plus a call for more critical thinking in medicine. Related Content: Stumbling Toward AI in the Clinic
Chatting With a Chatbot: The History of the First Clinical Chatbots, Straight From an LLM
A large language model (LLM) details the history of 2 early chatbots, ELIZA and PARRY, in conversation with JAMA+ AI Editor in Chief Roy Perlis. This podcast was recorded using OpenAI's ChatGPT in voice mode, via web interface, running on GPT-4o. Related Content: What Can 50-Year-Old Chatbots Teach Us About Clinical Applications of AI?
Seeing Health Through the Eye and AI
Retinal images are becoming powerful windows into human health. Cecilia Lee, MD, MS, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen to explore how AI-enhanced imaging reveals early disease signals, leverages large datasets, and shifts clinical practice in ophthalmology. Related Content: Insights From the Eye With AI
Multiple Reasoning Models and the Future of AI Chatbots
AI chatbots have advanced rapidly, incorporating new reasoning architectures that reshape decision-making and medical education. Jonathan Chen, MD, PhD, and Ethan Goh, MD, MS, of Stanford University join JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss the latest generation of AI models, the importance of evaluating benefits and harms, and sycophancy in AI systems. Related Con
Discussing the Latest Research in AI and Health
JAMA+ AI Editor in Chief Roy Perlis and Associate Editor Yulin Hswen discuss some of the most cited AI papers in 2025 across the JAMA Network. A little bit of gen AI, some prediction models, and deep learning from videos as well as an increasing awareness of the challenges of real-world deployment. Related Content: AI and Health—The Year in Review
Designing AI for Uncertainty: A Conversation With Eric Horvitz
How can AI systems reason safely in the open world of medicine? JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, talks with Eric Horvitz, MD, PhD, Chief Scientific Officer at Microsoft, about the future of AI in 5 years to 100 years, from neurons to the nebulous, and how we can guide AI to be copilots while maintaining integrity and safety in the clinical arena. Related Content: AI—Days of Futur
AI for Drug Discovery
Will AI usher in a new era of rapid drug discovery? In this episode of JAMA+ AI Conversations, Editor in Chief Roy Perlis interviews Ajamete Kaykas, Chief eXploration Officer at Insitro, a biotech company looking to apply AI to develop new therapeutics. Related Content: AI in the Lab—Will It Really Change Drug Discovery?
AI, Health, and Health Care
Derek Angus, MD, MPH, joins JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, to discuss a special communication from JAMA Summit: Artificial Intelligence. Related Content: What the Experts Think About Where AI Is Headed AI, Health, and Health Care Today and Tomorrow
AI, Health Care, and What to Expect in 2026
How will 2026 shape the world of AI in health? Editor in Chief Roy Perlis and Associate Editor Yulin Hswen discuss in this special episode marking one year since the launch of JAMA+ AI. Hosted by Roy H. Perlis, MD, MSc and Yulin Hswen, ScD, MPH. Related Content: What Will Next Year Bring for AI in Health? Detection of Epileptogenic Focal Cortical Dysplasia Using Graph Neural Networks Evaluating
Maintaining Safety and Trust When Patients Engage Google: A Conversation With Dr Michael Howell
How is Google Search evolving with AI and how do we ensure that language models maintain safety? JAMA+ AI Editor in Chief Roy Perlis, MD, talks with Michael Howell, MD, chief health officer at Google, about how he aims to balance innovation and safety in AI-driven medicine, building on his own work in hospital-based quality and safety. Related Content: "15% of Searches Have Never Been Typed Befo
AI in Women's Health
In this special edition of JAMA+ AI Conversations, editor in chief Roy Perlis is joined by Linda Brubaker, editor in chief of JAMA+ Women's Health and deputy editor at JAMA. They speak with Linda Moy, inaugural vice chair of AI for the NYU Department of Radiology and former editor of Radiology, about the opportunities and risks of applying AI in medical imaging. Will these new tools be a net posit
Navigating Transparency and Trust With AI in Health Care
Michelle Mello, JD, PhD, MPhil, professor of law and health policy at Stanford University, joins JAMA+ AI Editor in Chief Roy Perlis, MD, MSc, to discuss her recently published JAMA Perspective that lays out a framework for when and how health care organizations should disclose AI use to patients. Dr Mello shares insights on the importance of patient trust and surveys that suggest many patients cu
Changing Opinions About AI in Health Care
In this episode of JAMA+ AI Conversations, Microsoft CMO David Rhew, MD, discusses his journey from clinical practice to technology leadership, rapid progress in AI, its potential impacts on health care, and the challenges and opportunities that lie ahead for clinicians and researchers. Related Content: Changing Opinions About AI in Health Care
From the JAMA Network: Socially Assistive Robots, Part 2
In this follow-up to a 2017 interview with JAMA Medical News, the University of Southern California's Maja Matarić, PhD, the computer scientist who pioneered the field of socially assistive robotics, discusses how artificial intelligence is advancing the field in areas ranging from autism to physical rehabilitation to anxiety and depression. Related Content: Social Robots That Help Support Peopl
Can AI Improve Cost-Effectiveness of 3D Total-Body Photography?
3D total-body photography is used to detect lesions and melanoma in patients at high risk of developing skin cancer. The cost-effectiveness of this technology was examined in a recent study published in JAMA Dermatology. Roy Perlis, Editor in Chief of JAMA+ AI, joins economist Daniel Lindsay, PhD, to discuss the clinical and economic outcomes of this recent study. Related Content: Cost-Effective
Checking in Between Checkups: An AI App to Track Asthma Symptoms
Despite recommendations from health care professionals, most patients with asthma do not track their symptoms, leaving limited data to help them discuss care options with their clinicians. JAMA Associate Editor Yulin Hswen, ScD, MPH, spoke with Robert S. Rudin, PhD, a senior information scientist at RAND, and a professor of policy analysis at the Pardee RAND Graduate School, about a randomized cli
Harnessing AI and Genomics in Clinical Trial Enrollment
The Dana-Farber Cancer Institute (DFCI)'s MatchMiner tool was developed to increase historically low clinical trial enrollment rates in adults with cancer. Roy Perlis, MD, MSc, Editor in Chief of JAMA+ AI, spoke with Kenneth Kehl, MD, MPH, about his recent study published in JAMA Network Open evaluating the AI tool's ability to fulfill its purpose through genome sequencing. Related Content: Clin
AI-Based Analysis for Parkinsonism
Delaying diagnosis of parkinsonism can mean delaying care. In a study recently published in JAMA Neurology, David Vaillancourt, PhD, and colleagues tested the ability of an AI model to differentiate between Parkinson disease and other neurodegenerative disorders when paired with MRI. He joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH to discuss. Related Content: A Large Proportion
Should Employers Offer Digital Mental Health Programs to Support Workforce Well-Being?
Employer-sponsored digital health solutions help patients with behavioral health conditions increase workplace productivity. Yulin Hswen, ScD, MPH, Associate Editor of JAMA+ AI, spoke with Molly Candon, PhD, and Adam Chekroud, PhD, about their recent work published in JAMA Network Open evaluating the financial return on investment for companies participating in these AI health care programs. Rela
When Do Nudges Help?
Susan Athey, PhD, of Standford University joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her research on machine learning to target behavioral nudges for college students and their potential implications for health care. Related Content: How an Economist's Application of Machine Learning to Target Nudges Applies to Precision Medicine
Real-World Performance of AI in Screening for Diabetic Retinopathy
Diabetic retinopathy remains a leading cause of preventable blindness worldwide, and AI may facilitate screening, if such models continue to perform well when they are deployed in the real world. Coauthors Arthur Brant, MD, of Stanford University, and Sunny Virmani, MS, of Google join JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a new study published in JAMA Network Open. Related C
Can Open-Source LLMs Compete With Proprietary Ones for Complex Diagnoses?
A recent study published in JAMA Health Forum suggests that institutions may be able to deploy custom open-source large language models (LLMs) that run locally without sacrificing data privacy or flexibility. Coauthors Thomas A. Buckley, BS, and Arjun K. Manrai, PhD, from the Department of Biomedical Informatics at Harvard Medical School join JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to dis
Rethinking Race in Prenatal Screening for Open Neural Tube Defects
Correction: This podcast has been updated to add additional context on the frequency of false positives. Open neural tube defects affect approximately 1 in 1400 births. Daniel Herman, MD, PhD, of the University of Pennsylvania Perelman School of Medicine joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a quality improvement study examining the need to continue to incorporate race
AI's Role in Advancing Equity for Individuals With Developmental Disabilities
Artificial intelligence (AI) in health care is advancing, despite concerns about how its use may impact health disparities. Dimitri Christakis, MD, MPH, chief health officer at Special Olympics, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss AI's potential role in improving health care delivery for people with intellectual and developmental disabilities. Related Content: How AI Co
Prescreening for Clinical Trial Eligibility Using Large Language Models
A recent study showed AI-assisted screening using a large language model tool reduced time to determine trial eligibility compared with manual methods. Author Alexander J. Blood, MD, MSc, cardiologist at Brigham and Women's Hospital, and Associate Director of the Accelerator for Clinical Transformation Research Group at Harvard Medical School joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to d
Machine Learning for Earlier Diagnosis of Schizophrenia
In a recent study published in JAMA Psychiatry, researchers reported that a machine learning model was able to stratify risk for subsequent diagnosis of schizophrenia or bipolar disorder among individuals already receiving psychiatric treatment. Coauthor Søren Dinesen Østergaard, PhD, of Aarhus University in Denmark joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss. Related Conten
Language Equity in Health Technology
AI can play a role in addressing language barriers in health care. In a recent Editorial in JAMA Network Open, Pilar Ortega, MD, MGM, of the University of Illinois College of Medicine, and coauthors emphasized the urgent need for integrating language equity into digital health solutions. Dr Ortega joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss. Related Content: Resear
AI Guided Diagnostic-Quality Lung Ultrasound
Lung ultrasound aids in the diagnosis of patients with dyspnea but requires technical proficiency for image acquisition. Cristiana Baloescu, MD, MPH, of Yale School of Medicine, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss a new study published in JAMA Cardiology evaluating the ability of AI to guide acquisition of diagnostic-quality lung ultrasound images by trained health care p
Diagnosis and Treatment of Infectious Disease Using AI
A recent study in JAMA Network Open evaluates the use of machine learning algorithms to assess the management of urinary tract infection (UTI). Author Sanjat Kanjilal, MD, MPH, professor in the Department of Population Medicine at Harvard Medical School and Harvard Pilgrim Healthcare Institute, joins JAMA Associate Editor Yulin Hswen, ScD, MPH, to discuss this topic and more. Related Content: Re
Older Adults' Use of Digital Health Technology
Digital health technologies, including patient portals, are widely used by older adults, as described in a recent study published in JAMA Network Open. Author Cornelius James, MD, of the University of Michigan joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss the study and how it fits with his own experience in the clinic. Related Content: Study Finds Most Older Adults Use Digita
Patient Satisfaction With AI-Generated Responses
How do patients feel about the quality of AI-generated responses to their messages to clinicians? Author Eleni Linos, MD, DrPH, of Stanford joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her recent study in JAMA Network Open that characterized satisfaction with these messages. Related Content: Study Finds People Prefer AI Over Clinician Responses to Questions in the Electronic
Drafting Replies to Patient Messages With AI
The burden of responding to clinician inbox messages may be a contributor to burnout. Eden English, MD, of UCHealth joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss her recent study published in JAMA Network Open, which examined the use of large language models to reply to patient messages. Related Content: Researchers Tested an AI Tool That Drafts Responses to Patient Messages—
Bioethics and AI
With accelerating global adoption of AI, countries are developing ethical AI frameworks to prevent harm to the most vulnerable populations. Maria Villalobos-Quesada, PhD, from the National eHealth Living Lab (NeLL) in the Netherlands and the Observatory of Bioethics and Law of the University of Barcelona, discusses this and more with JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH. *Author image
AI-Based Suicide Screening for American Indian Patients
American Indian and Alaska Native communities have higher rates of suicide than any other racial or ethnic group in the US. A recent study published in JAMA Network Open describes an AI-based suicide screening tool investigated in an American Indian community. Author Emily Haroz, PhD, of Johns Hopkins Bloomberg School of Public Health, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH
Comparing Early Hospital Warning Scores for Clinical Deterioration
How can hospitals use early warning score tools to risk stratify patients without adding to alarm fatigue? Dana Edelson, MD, MS, of the University of Chicago joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss a recent study published in JAMA Network Open that she coauthored, comparing 6 early warning scores designed to recognize clinical deterioration in hospitalized patients. Rela
AI Chatbots in Clinical Practice
Chatbots may have a role in enhancing clinical care, but the best way to apply them remains a work in progress. Jonathen Chen, MD, PhD, and Ethan Goh, MD, MS, of Stanford, join JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss their randomized clinical trial published in JAMA Network Open investigating the use of chatbots in clinical practice. Related Content: An AI Chatbot Ou
How Health Systems Can Collaborate on AI Tools
In a recent Viewpoint published in JAMA, Michael Pencina, PhD, of Duke University, argued for a federated registration system for AI tools deployed in health systems. He joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss his article, the Coalition for Health AI (CHAI), and more. Related Content: Health Systems Are Struggling to Keep Up With AI—A National Registration System Could
AI-Enabled Ultrasound Could Improve Global Obstetric Care
In resource-limited settings, an integrated AI tool allows novice users to improve gestational age estimates. Jeffrey Stringer, MD, University of North Carolina, joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss "Diagnostic Accuracy of an Integrated AI Tool to Estimate Gestational Age From Blind Ultrasound Sweeps." Related Content: The Low-Cost, Battery-Powered AI-Enabled Ultraso
AI as Interpreter in the Clinic
Effective communication is essential in medicine, yet language barriers can result in suboptimal care. AI holds promise for bridging these gaps, enhancing outcomes, and reducing disparities. Casey Lion, MD, MPH, from the University of Washington School of Medicine, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss AI as an interpreter in the clinic. Related Content: Rese
AI and the FDA
A recent Special Communication published in JAMA points out that the FDA has already approved nearly 1000 devices using AI. Author Robert M. Califf, MD, commissioner of the US Food and Drug Administration, joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss AI regulation. Related Content: FDA Commissioner Robert Califf on Setting Guardrails for AI in Health Care JAMA AI Interview W
The Ethics of AI as Clinical Decision Maker
A recent JAMA Cardiology essay argues that medicine is not just a technical endeavor, it's also a moral endeavor, and a robot does not have moral agency. Coauthor Sarah C. Hull, MD, MBE, of Yale School of Medicine, joins JAMA and JAMA+ AI Associate Editor Yulin Hswen, ScD, MPH, to discuss the use of AI in managing decision-making in cardiac care. Related Content: AI Can't Worry About Patients, a
AI and the National Academy of Sciences
Widespread adoption of AI raises questions about accountability, transparency, and reproducibility. Marcia McNutt, PhD, president of the National Academy of Sciences, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss advancing scientific knowledge in the age of AI. Related Content: National Academies President on How to Use Generative AI Responsibly in Scientific Resea
Getting Technology Into the Clinic
Getting genuinely useful new technologies, from wearables to clinical decision support, into the clinic has proven to be surprisingly challenging. Tanzeem K. Choudhury, PhD, of Cornell Tech joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss how to take research into the real world in a way that is scalable and affordable. Related Content: How Health and Technology Sectors Can Coll
What Lessons Does the VA's Experience Building Electronic Health Records Hold for AI?
What hard lessons did the US Department of Veterans Affairs (VA) learn in 3 decades of EHR development, and what can it teach us about building better AI in medicine? Stephen Fihn, MD, MPH, of the University of Washington, and formerly a leader in the VA's EHR efforts, joins JAMA+ AI Editor in Chief Roy H. Perlis, MD, MSc, to discuss his experience at the VA building decision support tools and oth
The Future of Wearables and Mobile Devices for Patient Care
Can data from wearable devices and electronic health records enhance quality improvement in health care? In this Q&A, Sachin Kheterpal, MD, MBA, the University of Michigan Medical School Associate Dean for Research Information Technology, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the potential of data from mobile devices to revolutionize patient care. Related Co
AI in Radiology: Enhancing Analysis, Education, and Access
Can AI augment radiological processes, imaging analysis, and diagnosis? In this Q&A, Saurabh Jha, MBBS, MRCS, MS, an associate professor of radiology at the University of Pennsylvania, joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss how AI could play a crucial role in improving access to medical imaging in remote, high-altitude, and low-income areas. Related Content
Enhancing Global Mental Health Care With Digital Tools and AI for Scalable Interventions
Can AI/machine learning-driven digital phenotyping facilitate global personalized medicine? In this Q&A, Vikram Patel, MBBS, PhD, the Paul Farmer Professor and chair of the Department of Global Health and Social Medicine at Harvard Medical School, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss how AI can enhance assessment and treatment solutions across lower-income n
Using AI to Increase Access to Reliable Health Information
Could generative AI assist in extending access to vulnerable populations and begin to bridge the gap in disparities? In this Q&A, Davey Smith, MD, MAS, an infectious disease specialist and virologist at the University of California, San Diego, joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to explore the implications of large language models for improving patient outcomes. Re
The Potential for AI to Enable Speech and Facilitate Full Expression for Individuals With Brain Injuries
AI can understand brain signals linked to the sensory and motor processes involved in speech. In this Q&A, Edward Chang, MD, the chair and professor of neurosurgery at UCSF joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss how AI has the potential to facilitate communication and how close AI development is to being able to translate human emotion. Related Content: Di
How AI Could Advance Human Heart Discoveries and Improve Care
Can AI enhance the speed and efficiency of interpreting ultrasounds and echocardiograms, thereby minimizing diagnostic errors? In this Q&A, Rima Arnaout, MD, a cardiologist and associate professor of medicine at the University of California-San Francisco, joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the transformative impact of AI on cardiac imaging. Related Cont
Automation Bias and Short Cuts in Clinical AI Models
Automation bias and shortcuts in clinical AI models have posed significant challenges. In this Q&A, Jenna Wiens, PhD, an associate professor of Computer Science and Engineering at the University of Michigan in Ann Arbor, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss how we can start leveraging human collaboration with AI to provide more effective health care. Relate
AI and the Ethics of Developing and Deploying Clinical AI Models
AI in clinical practice needs ethical frameworks to avert future biases. In this Q&A, Marzyeh Ghassemi, PhD, the Herman L. F. von Helmholtz Career Development Professor at MIT in Electrical Engineering and Computer Science (EECS), joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss ethical machine learning and responsible clinical implementation. Related Content: AI De
Discovery and Scaling Findings From Large, Multicenter Health Care Datasets
How can we leverage AI to transform health care into a more efficient model for delivering care? In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Atul Butte, MD, PhD, the director of the Bakar Computational Health Sciences Institute at UCSF, to discuss scalable privilege and the need for the broad distribution of AI-driven expertise. Related Content: "Scalable
AI Monitoring to Reduce Data-Based Disparities
Amid the surging buzz around artificial intelligence (AI), can we trust the Al hype, and more importantly, are we ready for its implications? In this Q&A, Arvind Narayanan, PhD, a professor of computer science at Princeton, joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the exploration of Al's fairness, transparency, and accountability. Related Content: How to Nav
AI Guardrails: The US Executive Order and the Need for Global Harmonization
Artificial intelligence holds the promise of revolutionizing disease diagnosis and prediction, but it also presents a pivotal challenge: ensuring equity. In this Q&A, Alondra Nelson, PhD, the Harold F. Linder Professor at the Institute for Advanced Study, joins JAMA's Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the equitable regulation of AI to benefit all populations. Relat
The AI Health Care Goal for Patient Care
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews John Ayers, PhD, MA, vice chief of innovation in the Division of Infectious Diseases & Global Public Health, deputy director of informatics in the Altman Clinical and Translational Research Institute, and affiliate scientist in the Qualcomm Institute, all at UC San Diego, to discuss how genAI programs like ChatGPT
The Learning Health System and AI
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Nigam Shah, MBBS, PhD, professor of medicine at Stanford University and chief data scientist at Stanford Health Care, to discuss how large language models are reshaping medicine and the potential pitfalls of automation. Related Content: Clinical AI Tools Must Be Fed the Right Data, Stanford Health Care's Chief Da
Predictive AI and Early Clinical Detection
AI has potential to meaningfully improve patient care. How will AI advances help clinicians focus on the best use of their time and talents? In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Suchi Saria, PhD, MSc, an associate professor in computer science at Johns Hopkins, to discuss how AI could streamline care. Related Content: Can Predictive AI Improve Early
Can AI Accelerate Medical Education?
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Bernard S. Chang, MD, MMSc, a neurologist and dean for medical education at Harvard Medical School, discuss how AI will change medical education, admissions, and teaching the future generation of physicians and clinicians. Related Content: AI Will—and Should—Change Medical School, Says Harvard's Dean for Medical Educati
Building Patient and Clinician Trust in a Health Care System
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, talks with Andrew Bindman, MD, an internist and the executive vice president and chief medical officer for Kaiser Permanente, about AI implementation and the importance of building trust in a health care system. Related Content: Kaiser Permanente's CMO: How AI Might Help Clinicians Address Patients' Social Risk Factors
Improving Health Care Quality and Equity
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, interviews Kedar S. Mate, MD, an internal medicine physician, President and Chief Executive Officer at the Institute for Healthcare Improvement, and faculty at Weill Cornell Medical College, to discuss AI's role in health care quality and approaches to improving health equity. Related Content: New AI Tools Must Have Health
The Potential to Reduce Clinician Burden and Streamline Health Systems
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Kevin B. Johnson, MD, MS, the David L. Cohen and Penn Integrates Knowledge University Professor of Pediatrics, Informatics, Engineering, and Communication at the University of Pennsylvania, discuss how AI can reduce clinician burden and streamline health system functions. Related Content: Electronic Health Records Faile
The Potential for AI to Augment Humanity in Medicine
In this Q&A, JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, and Ida Sim, MD, PhD, a primary care physician and UCSF's Chief Research Informatics Officer, discuss generative AI, large language models, and the ways in which AI could affect humanity in medicine. Related Content: The Promise and Pitfalls of AI in the Complex World of Diagnosis, Treatment, and Disease Management
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